Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2504..2973 Replicon plasmid unnamed1
Accession NZ_CP041755
Organism Pseudomonas sp. KBS0707

Toxin (Protein)


Gene name relE Uniprot ID Q48BA0
Locus tag FFH21_RS28700 Protein ID WP_002556029.1
Coordinates 2692..2973 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q48BA1
Locus tag FFH21_RS28695 Protein ID WP_002556028.1
Coordinates 2504..2692 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFH21_RS28680 1..1314 + 1314 WP_032489053.1 replication initiation protein -
FFH21_RS28685 1444..2324 - 881 Protein_1 transposase -
FFH21_RS28695 2504..2692 + 189 WP_002556028.1 hypothetical protein Antitoxin
FFH21_RS28700 2692..2973 + 282 WP_002556029.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FFH21_RS28705 3125..4672 - 1548 WP_041924905.1 glycoside hydrolase family 28 protein -
FFH21_RS28710 4756..4980 - 225 WP_041924893.1 carbon storage regulator -
FFH21_RS28715 5084..5266 - 183 WP_004661237.1 hypothetical protein -
FFH21_RS28720 5696..6010 - 315 WP_081002620.1 hypothetical protein -
FFH21_RS28725 6109..6393 - 285 WP_011282457.1 type III effector HopW1-1, truncated -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..131974 131974
- flank IS/Tn - - 1420..2022 602


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10675.35 Da        Isoelectric Point: 8.4392

>T129159 WP_002556029.1 NZ_CP041755:2692-2973 [Pseudomonas sp. KBS0707]
MLPVVWLSPALDDLREIATYIAWENPSAARRLKSLLQEAIEPVAEHPYLYRSGRAPGTRELVAHPNYVLVYRVTLKRIEV
VNVIHARQEYPSP

Download         Length: 282 bp

>T129159 NZ_CP041755:2692-2973 [Pseudomonas sp. KBS0707]
ATGCTGCCGGTGGTCTGGCTCAGTCCCGCACTGGATGATCTGCGCGAAATCGCAACCTACATCGCATGGGAAAACCCGAG
CGCAGCGCGCCGGTTGAAAAGCCTCCTGCAGGAGGCTATCGAGCCGGTAGCCGAACACCCCTATTTATATCGTTCTGGGC
GAGCGCCAGGCACTCGCGAGCTGGTGGCTCACCCAAACTACGTCTTGGTCTATCGTGTCACCCTCAAGCGCATCGAGGTC
GTGAACGTAATCCACGCTAGGCAGGAATACCCCTCTCCCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7043.86 Da        Isoelectric Point: 4.2550

>AT129159 WP_002556028.1 NZ_CP041755:2504-2692 [Pseudomonas sp. KBS0707]
MANLSPIVSEFETDEQAASYDRWFRAKVAASLADPRPAIPHDEVMAEIEALIDQVETQREKR

Download         Length: 189 bp

>AT129159 NZ_CP041755:2504-2692 [Pseudomonas sp. KBS0707]
ATGGCCAACCTCTCACCCATCGTTTCAGAATTCGAAACCGATGAACAGGCCGCAAGCTACGACCGCTGGTTTCGCGCCAA
GGTCGCCGCCAGTCTGGCCGATCCGCGTCCGGCCATCCCTCATGATGAGGTCATGGCGGAAATAGAAGCGCTGATCGATC
AGGTTGAAACCCAACGTGAGAAACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M9HVA1

Antitoxin

Source ID Structure
AlphaFold DB A0A2G9KWB9

References