Detailed information of TA system TA129158

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RHH
• Location: 1976905..1977418
• Replicon: chromosome
• Accession: NZ_CP041754
• Organism: Pseudomonas sp. KBS0707

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FFH21_RS09270
• Protein ID: WP_004658391.1
• Coordinates: 1976905..1977189 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q48KT0
• Locus tag: FFH21_RS09275
• Protein ID: WP_011168200.1
• Coordinates: 1977179..1977418 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FFH21_RS09255	1973048..1974976	+	1929	WP_004665865.1	methyl-accepting chemotaxis protein	-
FFH21_RS09260	1975007..1975939	-	933	WP_041924491.1	DMT family transporter	-
FFH21_RS09265	1976014..1976868	+	855	WP_004658390.1	LysR family transcriptional regulator	-
FFH21_RS09270	1976905..1977189	-	285	WP_004658391.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FFH21_RS09275	1977179..1977418	-	240	WP_011168200.1	CopG family ribbon-helix-helix protein	Antitoxin
FFH21_RS09280	1977578..1978594	-	1017	WP_011168201.1	1-aminocyclopropane-1-carboxylate deaminase	-
FFH21_RS09285	1978781..1979287	+	507	WP_004658394.1	Lrp/AsnC family transcriptional regulator	-
FFH21_RS09290	1979437..1980345	+	909	WP_011168203.1	DUF808 domain-containing protein	-
FFH21_RS09300	1980524..1981296	-	773	Protein_1701	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-41)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10647.31 Da
• Isoelectric Point: 10.4249

>T129158 WP_004658391.1 NZ_CP041754:c1977189-1976905 [Pseudomonas sp. KBS0707]
MQVEWLKTALKNLDEEAAYIAQDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW

Nucleotide

• Length: 285 bp

>T129158 NZ_CP041754:c1977189-1976905 [Pseudomonas sp. KBS0707]
ATGCAGGTTGAGTGGCTTAAAACGGCGCTAAAGAATCTGGATGAGGAGGCAGCGTATATCGCACAGGACAATCCAGCTGC
TGCCGCAGCTTTCGTGAAAGCAATTCAATCAAGCGTGACGCAGCTCGCGAGCTTTCCCGCCATGGGCCGGGAAGGACGGA
TTGCCGGAACCAGAGAATGGCCTCTGCCAGACCTGCCTTACCTGATTCCATATCGCATCCGTAGCGGCCGGCTACAGGTT
CTAAGGATTTTCCACACCAGAAGACAATCGCCCCCCGTGTGGTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8688.78 Da
• Isoelectric Point: 4.4354

>AT129158 WP_011168200.1 NZ_CP041754:c1977418-1977179 [Pseudomonas sp. KBS0707]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASTEDVKAVMDKWSGNAG

Nucleotide

• Length: 240 bp

>AT129158 NZ_CP041754:c1977418-1977179 [Pseudomonas sp. KBS0707]
ATGTCCACAATGTCTCTACGTCTGCCGGACGAAATGGCGGATACCCTTGCACACCTTGCAAAGGCGACCGGGCGCAGCAA
GTCATTTTTGGCCCTCGACGCGCTCCGCGAATACCTGACTCGCGAGGCATGGCAGATTGCCGAAATTCAGCGCGCGATTG
AAGAAGCCGACGCTGGCGAGTTCGCCAGTACAGAGGACGTAAAAGCTGTCATGGACAAATGGTCTGGCAATGCAGGTTGA

Structures

Antitoxin

• AlphaFold DB: A0A3M6AYQ8