Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 99647..100166 Replicon chromosome
Accession NZ_CP041754
Organism Pseudomonas sp. KBS0707

Toxin (Protein)


Gene name relE Uniprot ID Q48Q48
Locus tag FFH21_RS00455 Protein ID WP_002551445.1
Coordinates 99876..100166 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag FFH21_RS00450 Protein ID WP_002551444.1
Coordinates 99647..99886 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFH21_RS00430 96399..97673 + 1275 WP_004667253.1 OprD family porin -
FFH21_RS00435 97707..98201 - 495 WP_004667254.1 hypothetical protein -
FFH21_RS00440 98362..98910 + 549 WP_004667255.1 GNAT family N-acetyltransferase -
FFH21_RS00445 99011..99484 + 474 WP_011167361.1 GNAT family N-acetyltransferase -
FFH21_RS00450 99647..99886 + 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FFH21_RS00455 99876..100166 + 291 WP_002551445.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FFH21_RS00460 100283..100660 + 378 Protein_84 transposase -
FFH21_RS00465 100821..101624 - 804 WP_011167363.1 IS21-like element ISPsy20 family helper ATPase IstB -
FFH21_RS00470 101617..102207 - 591 Protein_86 IS21 family transposase -
FFH21_RS00475 102722..103216 + 495 WP_011167365.1 type VI secretion system tube protein Hcp -
FFH21_RS00480 103229..104074 + 846 WP_011167366.1 hypothetical protein -
FFH21_RS00485 104085..104456 + 372 WP_019740508.1 hypothetical protein -
FFH21_RS00490 104595..104876 + 282 WP_041924381.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T129157 WP_002551445.1 NZ_CP041754:99876-100166 [Pseudomonas sp. KBS0707]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR

Download         Length: 291 bp

>T129157 NZ_CP041754:99876-100166 [Pseudomonas sp. KBS0707]
ATGACCTATAACCTCGAATTCGATGCGCGGGCTCTAAAGGAATGGCACAAATTAGGAGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCCAATCGTCTGCATGCATTGCCTGACTGCTACAAAATCA
AACTGCGCAGTAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCGGTAGACAAG
CGTGAACGGGAAGAGGTTTATCGCAAGGCGACGGACCGGCTGGGTAGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT129157 WP_002551444.1 NZ_CP041754:99647-99886 [Pseudomonas sp. KBS0707]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT129157 NZ_CP041754:99647-99886 [Pseudomonas sp. KBS0707]
ATGGCGTCTATCAACGTTCGTATCGACGACGATCTCAAAGCGCGTGCTTACCTCGAGCTGGAAAAGCTTGGCGTCACCCC
CTCGGAGTTGCTGCGCCAAACCCTGCAGTACGTAGCTGAGCGTGGTCAGCTACCCTTCAAGACGGTTCTGATGACAGAGG
AAGACGAAGCGCTGTTGGCAACTGTGCGCGAGCGCCTTGCAGCTCCGCAGCGGGTCAAGGTTTCACTGGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4DBS4

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References