Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 4922318..4923357 | Replicon | chromosome |
| Accession | NZ_CP041753 | ||
| Organism | Pseudomonas sp. ATCC 43928 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | FFH90_RS22415 | Protein ID | WP_138866116.1 |
| Coordinates | 4922782..4923357 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | A0A2S8HVM2 |
| Locus tag | FFH90_RS22410 | Protein ID | WP_018925078.1 |
| Coordinates | 4922318..4922785 (+) | Length | 156 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FFH90_RS22390 | 4918075..4918899 | + | 825 | WP_138866113.1 | ion transporter | - |
| FFH90_RS22395 | 4919006..4920004 | + | 999 | WP_019579599.1 | sulfate ABC transporter substrate-binding protein | - |
| FFH90_RS22400 | 4920062..4920694 | - | 633 | WP_138866114.1 | hypothetical protein | - |
| FFH90_RS22405 | 4920930..4922135 | + | 1206 | WP_138866115.1 | MFS transporter | - |
| FFH90_RS22410 | 4922318..4922785 | + | 468 | WP_018925078.1 | helix-turn-helix domain-containing protein | Antitoxin |
| FFH90_RS22415 | 4922782..4923357 | + | 576 | WP_138866116.1 | PIN domain-containing protein | Toxin |
| FFH90_RS22420 | 4923414..4923812 | - | 399 | WP_111454389.1 | hypothetical protein | - |
| FFH90_RS22425 | 4923827..4925035 | - | 1209 | WP_018925075.1 | c-type cytochrome biogenesis protein CcmI | - |
| FFH90_RS22430 | 4925028..4925501 | - | 474 | WP_018925074.1 | cytochrome c-type biogenesis protein CcmH | - |
| FFH90_RS22435 | 4925498..4926034 | - | 537 | WP_019648124.1 | DsbE family thiol:disulfide interchange protein | - |
| FFH90_RS22440 | 4926031..4928034 | - | 2004 | WP_018925072.1 | heme lyase CcmF/NrfE family subunit | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21810.95 Da Isoelectric Point: 5.6166
>T129154 WP_138866116.1 NZ_CP041753:4922782-4923357 [Pseudomonas sp. ATCC 43928]
VRHSPFTAVYDACVLYPAPLRDFLMWLALSGRFRARWSLEIHNEWKRNLLKNRPDLTTEQLDRTSDLMDQAIPDACVYGY
ERLIEGLTLPDVDDRHVLAAAIRCNASVIVTFNQKDFPDETLGPFGIEAQHPDEFVDNLFDLDPAAVVAAAQRQRKQLKM
PPMDVSTYLELLLRQGLTRSSKALTHYQAIL
VRHSPFTAVYDACVLYPAPLRDFLMWLALSGRFRARWSLEIHNEWKRNLLKNRPDLTTEQLDRTSDLMDQAIPDACVYGY
ERLIEGLTLPDVDDRHVLAAAIRCNASVIVTFNQKDFPDETLGPFGIEAQHPDEFVDNLFDLDPAAVVAAAQRQRKQLKM
PPMDVSTYLELLLRQGLTRSSKALTHYQAIL
Download Length: 576 bp
>T129154 NZ_CP041753:4922782-4923357 [Pseudomonas sp. ATCC 43928]
GTGAGGCACTCCCCTTTTACCGCTGTATATGACGCATGTGTTTTGTACCCCGCGCCCTTGAGAGATTTTCTGATGTGGCT
CGCGCTCTCCGGGCGTTTCAGGGCGCGATGGTCACTGGAGATACATAACGAATGGAAGCGCAATCTACTGAAGAACCGCC
CGGACCTGACAACAGAGCAGTTGGATCGCACGTCCGACTTGATGGATCAGGCCATACCTGATGCTTGCGTCTACGGTTAC
GAAAGGCTGATCGAAGGGCTAACCCTACCTGATGTCGATGACCGACATGTTCTGGCTGCCGCTATACGCTGCAATGCCAG
TGTCATTGTGACCTTTAATCAGAAAGATTTTCCTGACGAAACACTGGGACCTTTTGGCATCGAGGCCCAGCATCCTGACG
AGTTCGTCGATAACCTCTTCGATCTGGACCCGGCAGCAGTTGTTGCGGCAGCACAACGGCAACGCAAACAGCTAAAGATG
CCGCCGATGGATGTCAGCACTTATCTCGAACTGCTGTTGCGCCAAGGCCTGACTCGGTCGAGCAAGGCGTTGACCCACTA
TCAGGCCATTCTTTAA
GTGAGGCACTCCCCTTTTACCGCTGTATATGACGCATGTGTTTTGTACCCCGCGCCCTTGAGAGATTTTCTGATGTGGCT
CGCGCTCTCCGGGCGTTTCAGGGCGCGATGGTCACTGGAGATACATAACGAATGGAAGCGCAATCTACTGAAGAACCGCC
CGGACCTGACAACAGAGCAGTTGGATCGCACGTCCGACTTGATGGATCAGGCCATACCTGATGCTTGCGTCTACGGTTAC
GAAAGGCTGATCGAAGGGCTAACCCTACCTGATGTCGATGACCGACATGTTCTGGCTGCCGCTATACGCTGCAATGCCAG
TGTCATTGTGACCTTTAATCAGAAAGATTTTCCTGACGAAACACTGGGACCTTTTGGCATCGAGGCCCAGCATCCTGACG
AGTTCGTCGATAACCTCTTCGATCTGGACCCGGCAGCAGTTGTTGCGGCAGCACAACGGCAACGCAAACAGCTAAAGATG
CCGCCGATGGATGTCAGCACTTATCTCGAACTGCTGTTGCGCCAAGGCCTGACTCGGTCGAGCAAGGCGTTGACCCACTA
TCAGGCCATTCTTTAA
Antitoxin
Download Length: 156 a.a. Molecular weight: 17303.72 Da Isoelectric Point: 5.5294
>AT129154 WP_018925078.1 NZ_CP041753:4922318-4922785 [Pseudomonas sp. ATCC 43928]
MSPVIHPPLNLPMEREVQAAIEGQRALAAYLATQFETQHIQIFDEQNEAHSVELPTSALRLLVDILAELAAGNAVKVVPV
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFTDLMDYKTQRDIASEQAMTLLAEQAQALRTGYE
MSPVIHPPLNLPMEREVQAAIEGQRALAAYLATQFETQHIQIFDEQNEAHSVELPTSALRLLVDILAELAAGNAVKVVPV
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFTDLMDYKTQRDIASEQAMTLLAEQAQALRTGYE
Download Length: 468 bp
>AT129154 NZ_CP041753:4922318-4922785 [Pseudomonas sp. ATCC 43928]
ATGTCACCAGTTATCCATCCCCCCCTTAACCTGCCCATGGAGCGTGAGGTCCAGGCCGCTATCGAAGGTCAGCGCGCCTT
GGCTGCCTACCTCGCCACCCAATTCGAAACTCAGCATATCCAGATTTTCGATGAGCAGAATGAAGCACACAGCGTCGAAC
TTCCCACCTCAGCGCTTCGGTTGCTTGTCGACATCCTGGCAGAGCTCGCTGCAGGCAACGCCGTCAAAGTGGTCCCGGTA
CACGCTGAACTGACCACCCAGGAAGCGGCGGACTTGCTCAATGTCTCACGCCCGCACCTGATCAAACTGCTGGAGTCCGG
TGAGTTGTCCTACCACAAAACCGGCAAGCACCGACGTGTGCGCTTTACCGATTTGATGGACTATAAAACCCAGCGCGACA
TAGCCAGCGAGCAAGCAATGACGCTTCTCGCCGAGCAGGCACAAGCGTTAAGGACAGGATACGAGTGA
ATGTCACCAGTTATCCATCCCCCCCTTAACCTGCCCATGGAGCGTGAGGTCCAGGCCGCTATCGAAGGTCAGCGCGCCTT
GGCTGCCTACCTCGCCACCCAATTCGAAACTCAGCATATCCAGATTTTCGATGAGCAGAATGAAGCACACAGCGTCGAAC
TTCCCACCTCAGCGCTTCGGTTGCTTGTCGACATCCTGGCAGAGCTCGCTGCAGGCAACGCCGTCAAAGTGGTCCCGGTA
CACGCTGAACTGACCACCCAGGAAGCGGCGGACTTGCTCAATGTCTCACGCCCGCACCTGATCAAACTGCTGGAGTCCGG
TGAGTTGTCCTACCACAAAACCGGCAAGCACCGACGTGTGCGCTTTACCGATTTGATGGACTATAAAACCCAGCGCGACA
TAGCCAGCGAGCAAGCAATGACGCTTCTCGCCGAGCAGGCACAAGCGTTAAGGACAGGATACGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|