Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4268680..4269284 Replicon chromosome
Accession NZ_CP041753
Organism Pseudomonas sp. ATCC 43928

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FFH90_RS19495 Protein ID WP_018925564.1
Coordinates 4268680..4268973 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FFH90_RS19500 Protein ID WP_018925563.1
Coordinates 4268976..4269284 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFH90_RS19475 4263832..4265751 + 1920 WP_138867887.1 hypothetical protein -
FFH90_RS19480 4265783..4267006 + 1224 WP_138867888.1 GNAT family N-acetyltransferase -
FFH90_RS19485 4266978..4267790 + 813 WP_138867889.1 ChbG/HpnK family deacetylase -
FFH90_RS19490 4267847..4268536 + 690 WP_086944968.1 N-acetyltransferase -
FFH90_RS19495 4268680..4268973 + 294 WP_018925564.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FFH90_RS19500 4268976..4269284 + 309 WP_018925563.1 putative addiction module antidote protein Antitoxin
FFH90_RS19505 4269299..4270111 - 813 WP_138867890.1 class I SAM-dependent methyltransferase -
FFH90_RS19510 4270226..4271107 - 882 WP_064618753.1 LysR family transcriptional regulator -
FFH90_RS19515 4271268..4272284 + 1017 WP_138867891.1 alpha/beta hydrolase -
FFH90_RS19520 4272348..4273775 + 1428 WP_138867892.1 mechanosensitive ion channel family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10691.33 Da        Isoelectric Point: 10.9839

>T129153 WP_018925564.1 NZ_CP041753:4268680-4268973 [Pseudomonas sp. ATCC 43928]
MNYLIQQTTIFVAWHASIRDLRAKVAIARRIDRASTGNLGDIKSVGDGVSEMRVDVGAGYRVYFTLRNGVVIVLLAGGDK
SSQNTDIRRAKKLAREV

Download         Length: 294 bp

>T129153 NZ_CP041753:4268680-4268973 [Pseudomonas sp. ATCC 43928]
ATGAATTATCTTATTCAACAAACCACAATCTTCGTGGCATGGCATGCCTCAATTCGCGACTTGCGGGCGAAGGTTGCTAT
TGCTCGTCGCATTGACCGTGCCTCTACGGGTAATCTTGGCGATATCAAATCGGTGGGTGATGGTGTCTCCGAAATGCGCG
TGGACGTTGGCGCTGGCTATCGGGTCTACTTCACTTTGCGAAATGGCGTAGTCATCGTATTGCTGGCCGGTGGTGACAAG
TCCTCGCAAAACACTGATATCCGACGGGCGAAAAAATTGGCAAGGGAGGTTTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10913.43 Da        Isoelectric Point: 5.0344

>AT129153 WP_018925563.1 NZ_CP041753:4268976-4269284 [Pseudomonas sp. ATCC 43928]
MGQTLTAFDMAALLDSDEAISEYLSQVLADGDNEEFLRAIGYVVKARGMTQIAKDSGMGRESLYKAFAPGAKPRFDTVLK
VIHALGIDLCAQPGHAANHSTL

Download         Length: 309 bp

>AT129153 NZ_CP041753:4268976-4269284 [Pseudomonas sp. ATCC 43928]
ATGGGCCAGACTTTGACTGCTTTCGACATGGCGGCACTGCTCGACAGTGACGAAGCCATCAGCGAATACCTCTCTCAGGT
ATTGGCAGACGGCGACAACGAAGAGTTTCTTCGTGCTATCGGCTACGTGGTAAAGGCTCGCGGCATGACACAAATTGCCA
AAGATTCCGGAATGGGGCGCGAAAGCCTGTACAAGGCCTTCGCACCCGGGGCGAAACCACGTTTTGATACGGTTCTAAAG
GTCATTCATGCCTTGGGCATTGATCTCTGCGCGCAACCAGGGCACGCGGCAAATCACTCAACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References