Detailed information of TA system TA129152

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 1339889..1340394
• Replicon: chromosome
• Accession: NZ_CP041753
• Organism: Pseudomonas sp. ATCC 43928

Toxin (Protein)

• Gene name: relE
• Uniprot ID: J2N6H1
• Locus tag: FFH90_RS06015
• Protein ID: WP_007940443.1
• Coordinates: 1339889..1340143 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: FFH90_RS06020
• Protein ID: WP_007940444.1
• Coordinates: 1340140..1340394 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FFH90_RS05995	1335878..1336594	+	717	WP_086946438.1	peptide-methionine (S)-S-oxide reductase MsrA	-
FFH90_RS06000	1336610..1337623	-	1014	WP_064616222.1	sensor domain-containing diguanylate cyclase	-
FFH90_RS06005	1337699..1338604	-	906	WP_138866847.1	LysR family transcriptional regulator	-
FFH90_RS06010	1338707..1339882	+	1176	WP_019651780.1	aspartate aminotransferase family protein	-
FFH90_RS06015	1339889..1340143	-	255	WP_007940443.1	Txe/YoeB family addiction module toxin	Toxin
FFH90_RS06020	1340140..1340394	-	255	WP_007940444.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
FFH90_RS06025	1340622..1341149	-	528	WP_138866848.1	adenylate kinase	-
FFH90_RS06030	1341166..1343103	-	1938	WP_138866849.1	alkaline phosphatase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9997.52 Da
• Isoelectric Point: 8.0472

>T129152 WP_007940443.1 NZ_CP041753:c1340143-1339889 [Pseudomonas sp. ATCC 43928]
MNIEFTPEGWDDYLWFQQNDKAGLKRINLLIKAILREPFEGLGKPEPLKHNLSGLWSRRITSEHRLVYAIENGEVRIVLC
RYHY

Nucleotide

• Length: 255 bp

>T129152 NZ_CP041753:c1340143-1339889 [Pseudomonas sp. ATCC 43928]
ATGAATATCGAGTTCACTCCTGAAGGCTGGGACGACTATTTGTGGTTTCAGCAAAACGATAAGGCCGGGCTCAAACGAAT
CAACCTGCTGATCAAGGCGATCCTCCGTGAGCCCTTCGAAGGATTGGGCAAACCTGAACCGCTCAAACACAATCTGAGCG
GCCTCTGGTCACGCCGAATCACCTCCGAGCATCGCCTGGTTTATGCAATCGAGAATGGTGAGGTGCGCATCGTGCTTTGC
AGGTATCACTACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9500.94 Da
• Isoelectric Point: 8.5163

>AT129152 WP_007940444.1 NZ_CP041753:c1340394-1340140 [Pseudomonas sp. ATCC 43928]
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGNLRAGKTKVRQ
LIEE

Nucleotide

• Length: 255 bp

>AT129152 NZ_CP041753:c1340394-1340140 [Pseudomonas sp. ATCC 43928]
ATGCAAACCATCAACTACACCACCGCACGTGCACATCTGGCCGAAACCATGGATCGGGTCAACGAAGACCGTGCCCCATT
GCTGGTTACCCGCCAGAAAGGCGAACCTGTGGTGATGATGTCTCTGGCGGAGTACAACGCTCTCGAAGAGACAGCCTATC
TGCTCCGTTCTCCAGCCAATGCCGAACGACTGATCAAATCAATCGGCAACCTACGAGCAGGGAAAACCAAAGTCAGGCAA
CTCATCGAAGAATGA

Structures

Toxin

• AlphaFold DB: J2N6H1