Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2099838..2100429 Replicon chromosome
Accession NZ_CP041745
Organism Paraburkholderia megapolitana strain LMG 23650

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FNZ07_RS22660 Protein ID WP_091016621.1
Coordinates 2100136..2100429 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FNZ07_RS22655 Protein ID WP_091016619.1
Coordinates 2099838..2100134 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNZ07_RS22640 2095339..2097489 + 2151 WP_091016615.1 TonB-dependent siderophore receptor -
FNZ07_RS22650 2097827..2099758 + 1932 WP_091016617.1 SurA N-terminal domain-containing protein -
FNZ07_RS22655 2099838..2100134 - 297 WP_091016619.1 putative addiction module antidote protein Antitoxin
FNZ07_RS22660 2100136..2100429 - 294 WP_091016621.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNZ07_RS22665 2100706..2101047 - 342 WP_091016623.1 hypothetical protein -
FNZ07_RS22670 2101069..2101857 - 789 WP_091016625.1 arylesterase -
FNZ07_RS22675 2101856..2102542 + 687 WP_091016627.1 ABC transporter ATP-binding protein -
FNZ07_RS22680 2102703..2104328 - 1626 WP_091016629.1 glucose-6-phosphate isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(24-93)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10862.52 Da        Isoelectric Point: 9.9062

>T129120 WP_091016621.1 NZ_CP041745:c2100429-2100136 [Paraburkholderia megapolitana]
MRIEQTEVFVTWMRGLRDGVGRANIVKRIERLGNGNTGDVKAVGAGVIEMRIHYGPGYRVYYTQRGNVLVVLLCGGDKST
QQRDIEQAIRLAAELEK

Download         Length: 294 bp

>T129120 NZ_CP041745:c2100429-2100136 [Paraburkholderia megapolitana]
ATGCGTATCGAACAGACAGAAGTTTTCGTGACGTGGATGCGCGGACTGCGGGACGGGGTTGGCAGGGCCAACATCGTCAA
GCGTATCGAGCGGCTCGGAAACGGGAACACCGGCGACGTGAAGGCAGTCGGCGCCGGCGTCATCGAAATGCGAATCCACT
ATGGCCCCGGCTACCGGGTCTACTACACGCAGCGAGGCAATGTGTTGGTGGTCTTGTTATGTGGTGGCGACAAGTCGACG
CAGCAGCGCGACATCGAGCAAGCGATCCGGCTCGCAGCCGAACTGGAGAAATGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10552.84 Da        Isoelectric Point: 4.8000

>AT129120 WP_091016619.1 NZ_CP041745:c2100134-2099838 [Paraburkholderia megapolitana]
MGIKTTPFDAADYLDTPEAQGEYLRLSFESEDPGEIQEALGTVARARGMSQIARDAGVGRESLYKALSGTGNPEFATVIR
VLHALGLHLTVTPRHDPV

Download         Length: 297 bp

>AT129120 NZ_CP041745:c2100134-2099838 [Paraburkholderia megapolitana]
ATGGGAATCAAGACGACGCCATTTGACGCGGCGGACTACCTGGACACGCCGGAAGCACAGGGCGAGTACCTTCGCCTCTC
CTTCGAATCCGAAGATCCCGGCGAGATCCAGGAGGCGCTCGGCACGGTCGCGCGCGCGCGCGGTATGTCGCAGATTGCAC
GCGATGCCGGCGTCGGCCGCGAGAGTCTGTATAAGGCGCTGAGCGGAACCGGAAATCCCGAGTTTGCGACGGTTATTCGC
GTGCTTCACGCGCTTGGTCTGCATCTGACCGTGACGCCTCGGCACGATCCGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References