Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2099838..2100429 Replicon chromosome
Accession NZ_CP041745
Organism Paraburkholderia megapolitana strain LMG 23650

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FNZ07_RS22660 Protein ID WP_091016621.1
Coordinates 2100136..2100429 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FNZ07_RS22655 Protein ID WP_091016619.1
Coordinates 2099838..2100134 (-) Length 99 a.a.

Genomic Context

FNZ07_RS22640FNZ07_RS22650FNZ07_RS22675FNZ07_RS22655FNZ07_RS22660FNZ07_RS22665FNZ07_RS22670FNZ07_RS22680
Location: 2095339..2097489 (2151 bp)
Type: Others
Protein ID: WP_091016615.1
Location: 2097827..2099758 (1932 bp)
Type: Others
Protein ID: WP_091016617.1
Location: 2101856..2102542 (687 bp)
Type: Others
Protein ID: WP_091016627.1
Location: 2099838..2100134 (297 bp)
Type: Antitoxin
Protein ID: WP_091016619.1
Location: 2100136..2100429 (294 bp)
Type: Toxin
Protein ID: WP_091016621.1
Location: 2100706..2101047 (342 bp)
Type: Others
Protein ID: WP_091016623.1
Location: 2101069..2101857 (789 bp)
Type: Others
Protein ID: WP_091016625.1
Location: 2102703..2104328 (1626 bp)
Type: Others
Protein ID: WP_091016629.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FNZ07_RS226402095339..2097489+2151WP_091016615.1TonB-dependent siderophore receptor-
FNZ07_RS226502097827..2099758+1932WP_091016617.1SurA N-terminal domain-containing protein-
FNZ07_RS226552099838..2100134-297WP_091016619.1putative addiction module antidote proteinAntitoxin
FNZ07_RS226602100136..2100429-294WP_091016621.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FNZ07_RS226652100706..2101047-342WP_091016623.1hypothetical protein-
FNZ07_RS226702101069..2101857-789WP_091016625.1arylesterase-
FNZ07_RS226752101856..2102542+687WP_091016627.1ABC transporter ATP-binding protein-
FNZ07_RS226802102703..2104328-1626WP_091016629.1glucose-6-phosphate isomerase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(24-93)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10862.52 Da        Isoelectric Point: 9.9062

>T129120 WP_091016621.1 NZ_CP041745:c2100429-2100136 [Paraburkholderia megapolitana]
MRIEQTEVFVTWMRGLRDGVGRANIVKRIERLGNGNTGDVKAVGAGVIEMRIHYGPGYRVYYTQRGNVLVVLLCGGDKST
QQRDIEQAIRLAAELEK

Download         Length: 294 bp

>T129120 NZ_CP041745:c2100429-2100136 [Paraburkholderia megapolitana]
ATGCGTATCGAACAGACAGAAGTTTTCGTGACGTGGATGCGCGGACTGCGGGACGGGGTTGGCAGGGCCAACATCGTCAA
GCGTATCGAGCGGCTCGGAAACGGGAACACCGGCGACGTGAAGGCAGTCGGCGCCGGCGTCATCGAAATGCGAATCCACT
ATGGCCCCGGCTACCGGGTCTACTACACGCAGCGAGGCAATGTGTTGGTGGTCTTGTTATGTGGTGGCGACAAGTCGACG
CAGCAGCGCGACATCGAGCAAGCGATCCGGCTCGCAGCCGAACTGGAGAAATGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10552.84 Da        Isoelectric Point: 4.8000

>AT129120 WP_091016619.1 NZ_CP041745:c2100134-2099838 [Paraburkholderia megapolitana]
MGIKTTPFDAADYLDTPEAQGEYLRLSFESEDPGEIQEALGTVARARGMSQIARDAGVGRESLYKALSGTGNPEFATVIR
VLHALGLHLTVTPRHDPV

Download         Length: 297 bp

>AT129120 NZ_CP041745:c2100134-2099838 [Paraburkholderia megapolitana]
ATGGGAATCAAGACGACGCCATTTGACGCGGCGGACTACCTGGACACGCCGGAAGCACAGGGCGAGTACCTTCGCCTCTC
CTTCGAATCCGAAGATCCCGGCGAGATCCAGGAGGCGCTCGGCACGGTCGCGCGCGCGCGCGGTATGTCGCAGATTGCAC
GCGATGCCGGCGTCGGCCGCGAGAGTCTGTATAAGGCGCTGAGCGGAACCGGAAATCCCGAGTTTGCGACGGTTATTCGC
GTGCTTCACGCGCTTGGTCTGCATCTGACCGTGACGCCTCGGCACGATCCGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References