Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 505281..505920 Replicon chromosome
Accession NZ_CP041743
Organism Paraburkholderia megapolitana strain LMG 23650

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FNZ07_RS02105 Protein ID WP_091007785.1
Coordinates 505281..505697 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FNZ07_RS02110 Protein ID WP_091007788.1
Coordinates 505684..505920 (-) Length 79 a.a.

Genomic Context

FNZ07_RS02115FNZ07_RS02120FNZ07_RS02130FNZ07_RS02080FNZ07_RS02085FNZ07_RS02090FNZ07_RS02095FNZ07_RS02100FNZ07_RS02105FNZ07_RS02110FNZ07_RS02125
Location: 506211..507854 (1644 bp)
Type: Others
Protein ID: WP_091007791.1
Location: 508016..509290 (1275 bp)
Type: Others
Protein ID: WP_091007793.1
Location: 510061..510885 (825 bp)
Type: Others
Protein ID: WP_091007799.1
Location: 500815..501795 (981 bp)
Type: Others
Protein ID: WP_091007768.1
Location: 501815..502603 (789 bp)
Type: Others
Protein ID: WP_091007771.1
Location: 502658..503806 (1149 bp)
Type: Others
Protein ID: WP_091007775.1
Location: 503843..504979 (1137 bp)
Type: Others
Protein ID: WP_091007780.1
Location: 505044..505256 (213 bp)
Type: Others
Protein ID: WP_091007783.1
Location: 505281..505697 (417 bp)
Type: Toxin
Protein ID: WP_091007785.1
Location: 505684..505920 (237 bp)
Type: Antitoxin
Protein ID: WP_091007788.1
Location: 509300..509668 (369 bp)
Type: Others
Protein ID: WP_091007796.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FNZ07_RS02080500815..501795-981WP_091007768.1SDR family oxidoreductase-
FNZ07_RS02085501815..502603-789WP_091007771.1hydroxypyruvate isomerase family protein-
FNZ07_RS02090502658..503806-1149WP_091007775.1hypothetical protein-
FNZ07_RS02095503843..504979-1137WP_091007780.1hypothetical protein-
FNZ07_RS02100505044..505256-213WP_091007783.1type II toxin-antitoxin system VapB family antitoxin-
FNZ07_RS02105505281..505697-417WP_091007785.1type II toxin-antitoxin system VapC family toxinToxin
FNZ07_RS02110505684..505920-237WP_091007788.1DNA-binding proteinAntitoxin
FNZ07_RS02115506211..507854+1644WP_091007791.1hypothetical protein-
FNZ07_RS02120508016..509290+1275WP_091007793.1MFS transporter-
FNZ07_RS02125509300..509668-369WP_091007796.1hypothetical protein-
FNZ07_RS02130510061..510885+825WP_091007799.1IclR family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15482.75 Da        Isoelectric Point: 6.4845

>T129117 WP_091007785.1 NZ_CP041743:c505697-505281 [Paraburkholderia megapolitana]
VYLVDTNIVSEIRKKERCNKGVRAFFRQAVKSDIDLYLSVVTIGELRRGVEIVRHRGDVAQAASLEAWLTAVLNEFAQNI
LPVDEDIGQLWGRLRVPHPEHALDKLIAATGLIHDLTVVTRNVDDFSPTGVRVLNPFD

Download         Length: 417 bp

>T129117 NZ_CP041743:c505697-505281 [Paraburkholderia megapolitana]
GTGTATTTGGTTGATACCAACATCGTGAGCGAAATAAGAAAGAAAGAGCGCTGCAATAAAGGCGTGCGCGCTTTCTTCCG
GCAAGCAGTGAAGTCGGATATCGATCTGTATCTGTCCGTGGTCACCATTGGTGAACTGAGGCGTGGCGTCGAGATAGTTC
GACATCGGGGAGATGTGGCGCAAGCCGCATCCCTCGAGGCGTGGTTGACGGCGGTGCTCAACGAGTTCGCGCAGAACATT
CTCCCGGTGGACGAGGACATTGGGCAATTGTGGGGGAGACTACGCGTACCGCACCCGGAGCATGCGTTGGATAAGCTGAT
CGCGGCGACGGGGCTGATTCACGATCTGACTGTCGTGACGCGGAACGTCGATGATTTTTCGCCCACGGGGGTTCGTGTAT
TGAACCCGTTTGATTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8614.66 Da        Isoelectric Point: 5.6158

>AT129117 WP_091007788.1 NZ_CP041743:c505920-505684 [Paraburkholderia megapolitana]
MANLLVRGIDDALVQSLREQAAAHGRSAEAEHREILAHALRRPRKRSFAEVLMSMPDVGEDADFERVNDSGEAARVFG

Download         Length: 237 bp

>AT129117 NZ_CP041743:c505920-505684 [Paraburkholderia megapolitana]
ATGGCAAATCTTCTGGTTCGTGGGATTGATGATGCACTGGTGCAGAGCCTGCGTGAGCAGGCTGCTGCACATGGGCGCAG
CGCGGAGGCTGAGCACCGGGAAATCCTCGCGCATGCATTACGTCGCCCGAGAAAGCGCAGCTTTGCCGAGGTGTTGATGA
GTATGCCGGACGTGGGTGAGGATGCGGACTTTGAACGCGTGAATGATTCAGGTGAGGCCGCGCGTGTATTTGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References