Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3892249..3892906 Replicon chromosome
Accession NZ_CP041733
Organism Enterobacter hormaechei subsp. steigerwaltii strain ME-1

Toxin (Protein)


Gene name cptA Uniprot ID A0A179PSF7
Locus tag FO617_RS18970 Protein ID WP_017382887.1
Coordinates 3892249..3892659 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag FO617_RS18975 Protein ID WP_003863437.1
Coordinates 3892640..3892906 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FO617_RS18950 3888247..3889980 - 1734 WP_126804755.1 single-stranded-DNA-specific exonuclease RecJ -
FO617_RS18955 3889986..3890699 - 714 WP_023295380.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FO617_RS18960 3890728..3891624 - 897 WP_003863442.1 site-specific tyrosine recombinase XerD -
FO617_RS18965 3891726..3892247 + 522 WP_015571793.1 flavodoxin FldB -
FO617_RS18970 3892249..3892659 - 411 WP_017382887.1 protein YgfX Toxin
FO617_RS18975 3892640..3892906 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
FO617_RS18980 3893201..3894181 + 981 WP_048219529.1 tRNA-modifying protein YgfZ -
FO617_RS18985 3894293..3894952 - 660 WP_003863433.1 hemolysin III family protein -
FO617_RS18995 3895219..3895950 + 732 WP_015571796.1 MurR/RpiR family transcriptional regulator -
FO617_RS19000 3896067..3897500 + 1434 WP_017382891.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16321.21 Da        Isoelectric Point: 11.4775

>T129082 WP_017382887.1 NZ_CP041733:c3892659-3892249 [Enterobacter hormaechei subsp. steigerwaltii]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMMGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

>T129082 NZ_CP041733:c3892659-3892249 [Enterobacter hormaechei subsp. steigerwaltii]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGGCTGGTGGCGGC
ACTGGTGTTATTGGTGCCGTGGCCGCTTAGCTATACCCCTCTGTGGTTGCTATTGCTGTCGTTTGTGGTGTTTGACAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAGATGATGGGGACGCCGTGGATGCTTAATACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCTGCGGAGTGGCGAGATCTGCGCCGGTTGATCGTGCAACAGCCGA
CGCAGGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT129082 WP_003863437.1 NZ_CP041733:c3892906-3892640 [Enterobacter hormaechei subsp. steigerwaltii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT129082 NZ_CP041733:c3892906-3892640 [Enterobacter hormaechei subsp. steigerwaltii]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A179PSF7

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References