Detailed information of TA system TA129064

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-Xre
• Location: 5106981..5107981
• Replicon: chromosome
• Accession: NZ_CP041730
• Organism: Chitinimonas arctica strain R3-44

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: -
• Locus tag: FNU76_RS23175
• Protein ID: WP_144280396.1
• Coordinates: 5107505..5107981 (+)
• Length: 159 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: FNU76_RS23170
• Protein ID: WP_144280395.1
• Coordinates: 5106981..5107508 (+)
• Length: 176 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FNU76_RS23150	5102241..5102639	+	399	WP_144280392.1	hypothetical protein	-
FNU76_RS23155	5102649..5103725	+	1077	WP_144280393.1	hypothetical protein	-
FNU76_RS23160	5103783..5105098	-	1316	Protein_4537	AAA-associated domain-containing protein	-
FNU76_RS23165	5105112..5106848	-	1737	WP_144280394.1	ABC transporter permease subunit	-
FNU76_RS23170	5106981..5107508	+	528	WP_144280395.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
FNU76_RS23175	5107505..5107981	+	477	WP_144280396.1	RES family NAD+ phosphorylase	Toxin
FNU76_RS23180	5108200..5109279	+	1080	WP_144280546.1	IS630 family transposase	-
FNU76_RS23185	5109754..5110317	+	564	WP_144280397.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	5108200..5109279	1079

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (5-145)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (128-172)

Sequences

Toxin

Protein

• Length: 159 a.a.
• Molecular weight: 17206.79 Da
• Isoelectric Point: 7.2426

>T129064 WP_144280396.1 NZ_CP041730:5107505-5107981 [Chitinimonas arctica]
MSRQAWRIAADTPNYLADDLSGTGAKITGGRWNRAGIPLLYCAENIALACMETLVHTKASGLPLNRYLVRLEIPDPLWQA
AQRLTADSAPVGWDAVPVGKASLDFGDAWANSLASAVLLVPSVIVPDEHNILINPLHPDAARISATKLRRWLYDSRLL

Nucleotide

• Length: 477 bp

>T129064 NZ_CP041730:5107505-5107981 [Chitinimonas arctica]
TTGAGCCGGCAGGCCTGGCGCATTGCCGCGGACACGCCGAACTACCTGGCGGACGATCTGAGCGGGACAGGGGCCAAAAT
CACCGGTGGACGATGGAATCGCGCCGGCATCCCCCTGCTCTATTGCGCCGAGAATATTGCCCTGGCCTGCATGGAGACGC
TGGTACACACCAAGGCCAGCGGCCTGCCCCTGAATCGATACCTGGTCAGGCTGGAGATTCCCGACCCGCTCTGGCAGGCG
GCGCAACGGCTGACGGCGGACAGCGCACCGGTAGGATGGGATGCGGTGCCGGTCGGCAAGGCCAGCCTGGATTTCGGCGA
CGCCTGGGCCAACAGCCTGGCCTCCGCCGTCTTGCTGGTGCCCTCGGTGATCGTGCCTGACGAGCACAATATCCTGATCA
ATCCGCTCCACCCCGATGCCGCACGGATCAGCGCGACCAAGTTGCGACGGTGGTTGTACGATTCGCGGCTGCTTTAG

Antitoxin

Protein

• Length: 176 a.a.
• Molecular weight: 18809.64 Da
• Isoelectric Point: 7.9868

>AT129064 WP_144280395.1 NZ_CP041730:5106981-5107508 [Chitinimonas arctica]
MTSTVKKAPSPVKLPGGGPVSASRAAAAPALVVLTDFGEMYRSTPTRRVELIRQGVRAVELKDMVRLMDTSQDRVYKVLR
LSPATVNRKASRDEALSSEDSERVVGMSKLIGQVQTMVEQSGDPGGFDAAKWLAHWIEEPLPALGGACPADYMDTMEGIK
LVSNVLSTMQSGAYV

Nucleotide

• Length: 528 bp

>AT129064 NZ_CP041730:5106981-5107508 [Chitinimonas arctica]
ATGACAAGCACCGTCAAGAAAGCCCCGTCCCCCGTGAAATTGCCGGGAGGCGGACCCGTTTCGGCATCGCGCGCGGCGGC
CGCACCGGCGCTGGTCGTGCTGACGGACTTCGGCGAAATGTACCGCTCCACCCCGACCCGCCGCGTCGAGCTGATACGGC
AAGGTGTGCGCGCCGTCGAGCTGAAGGATATGGTCCGCCTGATGGATACCTCGCAGGACAGGGTCTACAAGGTCCTGCGC
CTGTCGCCCGCCACGGTAAACCGCAAGGCCAGCCGCGACGAAGCGCTATCCAGCGAGGACAGCGAGCGAGTGGTGGGGAT
GTCCAAGTTGATCGGGCAGGTGCAGACAATGGTGGAGCAGTCCGGCGATCCCGGCGGCTTCGATGCGGCGAAATGGCTGG
CGCATTGGATCGAGGAACCGCTCCCTGCCCTGGGCGGGGCTTGCCCCGCGGACTATATGGACACCATGGAAGGCATCAAG
CTGGTGTCCAACGTACTGTCGACCATGCAGAGCGGAGCCTACGTTTGA