Detailed information of TA system TA129063

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 5076922..5077472
• Replicon: chromosome
• Accession: NZ_CP041730
• Organism: Chitinimonas arctica strain R3-44

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FNU76_RS23045
• Protein ID: WP_144280372.1
• Coordinates: 5076922..5077197 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FNU76_RS23050
• Protein ID: WP_144280373.1
• Coordinates: 5077197..5077472 (-)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FNU76_RS23020	5073301..5074215	+	915	WP_144280367.1	sterol desaturase family protein	-
FNU76_RS23025	5074168..5074863	-	696	WP_179958259.1	AraC family transcriptional regulator	-
FNU76_RS23030	5074960..5075358	+	399	WP_144280369.1	DUF488 family protein	-
FNU76_RS23035	5075355..5076053	+	699	WP_144280370.1	aspartate/glutamate racemase family protein	-
FNU76_RS23040	5076118..5076888	+	771	WP_144280371.1	DUF1275 domain-containing protein	-
FNU76_RS23045	5076922..5077197	-	276	WP_144280372.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FNU76_RS23050	5077197..5077472	-	276	WP_144280373.1	ribbon-helix-helix domain-containing protein	Antitoxin
FNU76_RS23055	5077622..5078977	-	1356	WP_144280374.1	hypothetical protein	-
FNU76_RS23060	5079036..5081273	-	2238	WP_144280375.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10685.22 Da
• Isoelectric Point: 9.4316

>T129063 WP_144280372.1 NZ_CP041730:c5077197-5076922 [Chitinimonas arctica]
MQIKWTSKALSDLARLYEFLAPVNKAAAARTVQSLTVAPAALYEHPRLGERLEQFEPQEVRRLFVGHYELRYQAQGDTVY
VLRLWHTREER

Nucleotide

• Length: 276 bp

>T129063 NZ_CP041730:c5077197-5076922 [Chitinimonas arctica]
ATGCAGATCAAATGGACCTCAAAGGCTTTGTCCGATTTGGCTCGGCTTTATGAGTTCCTGGCACCAGTAAACAAAGCGGC
CGCAGCCCGAACCGTTCAATCGCTAACGGTTGCGCCTGCCGCTCTATATGAGCACCCGCGACTTGGTGAGCGGCTTGAAC
AATTCGAACCGCAAGAAGTACGGCGCCTCTTTGTTGGGCACTACGAGCTTCGCTATCAGGCTCAAGGAGACACCGTATAT
GTCCTACGACTATGGCATACCCGCGAGGAGAGGTAG

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 10140.36 Da
• Isoelectric Point: 5.0967

>AT129063 WP_144280373.1 NZ_CP041730:c5077472-5077197 [Chitinimonas arctica]
MSHADTKVVTAHLPRPLAERIDAVAARLDRSRGWIMKQALTAWLDQEEERDRLTREGLADVEAGNVIDHQAVQAWADSLG
TDQPFPLPTGR

Nucleotide

• Length: 276 bp

>AT129063 NZ_CP041730:c5077472-5077197 [Chitinimonas arctica]
ATGTCACACGCAGACACCAAAGTTGTCACAGCGCATTTGCCGCGACCGCTTGCGGAGCGCATCGACGCCGTGGCGGCCCG
CCTTGATCGCTCGCGTGGCTGGATCATGAAACAGGCGCTAACGGCATGGCTCGACCAGGAAGAAGAACGGGACCGGCTTA
CCCGCGAAGGACTCGCCGACGTCGAAGCCGGCAATGTGATCGATCACCAAGCGGTGCAGGCATGGGCCGATAGCCTGGGC
ACCGATCAACCATTTCCATTGCCGACGGGGCGCTGA