129062

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/ParE-RHH
Location 4469933..4470501 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FNU76_RS20430 Protein ID WP_144279912.1
Coordinates 4470211..4470501 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag FNU76_RS20425 Protein ID WP_144279911.1
Coordinates 4469933..4470223 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS20410 4466027..4468312 + 2286 WP_144279909.1 M9 family metallopeptidase -
FNU76_RS20415 4468524..4469189 + 666 WP_144280761.1 AraC family transcriptional regulator -
FNU76_RS20420 4469390..4469800 + 411 WP_144279910.1 hypothetical protein -
FNU76_RS20425 4469933..4470223 + 291 WP_144279911.1 ribbon-helix-helix protein, CopG family Antitoxin
FNU76_RS20430 4470211..4470501 + 291 WP_144279912.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNU76_RS20435 4470583..4470885 + 303 WP_144279913.1 Dabb family protein -
FNU76_RS20440 4470964..4471293 + 330 WP_144279914.1 DUF2185 domain-containing protein -
FNU76_RS20445 4471300..4471728 - 429 WP_144279915.1 BLUF domain-containing protein -
FNU76_RS20450 4471741..4472505 - 765 WP_144279916.1 GTP cyclohydrolase I -
FNU76_RS20455 4472547..4473185 - 639 WP_144279917.1 YceH family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-46)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10920.65 Da        Isoelectric Point: 9.6209

>T129062 WP_144279912.1 NZ_CP041730:4470211-4470501 [Chitinimonas arctica]
MSRLIWSRQALLDVQLLYRFLAGKNIDAAKRAVKAVRQGVIVLGHQPGVGRPIEDMPEEFREWVIDFGDSGYVARYRIDP
DAVTILAVRHQKEVGF

Download         Length: 291 bp

>T129062 NZ_CP041730:4470211-4470501 [Chitinimonas arctica]
ATGTCACGTCTGATCTGGTCGCGACAGGCGCTGCTCGATGTGCAGCTGCTCTATCGCTTCCTCGCCGGCAAGAACATCGA
TGCTGCTAAGCGCGCCGTCAAAGCTGTGCGGCAAGGAGTGATAGTGCTGGGGCACCAGCCAGGTGTCGGCCGCCCCATCG
AGGATATGCCAGAGGAGTTCCGGGAGTGGGTGATCGATTTCGGTGACAGCGGCTATGTGGCGCGCTACCGCATCGACCCG
GATGCCGTCACGATTCTCGCCGTGCGGCACCAAAAGGAGGTGGGCTTCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11240.66 Da        Isoelectric Point: 5.2451

>AT129062 WP_144279911.1 NZ_CP041730:4469933-4470223 [Chitinimonas arctica]
MTATVIRPVAIKIDEDIKARVKRLAEARHRTAHWLMREAITQYVEREEKREAFRQDTLKAWEEYRSTGLHVTADEADAWL
AELEQGNDIEPPECHV

Download         Length: 291 bp

>AT129062 NZ_CP041730:4469933-4470223 [Chitinimonas arctica]
ATGACTGCTACTGTCATTCGCCCGGTGGCGATCAAGATTGACGAGGACATCAAAGCACGTGTGAAGCGTTTGGCCGAAGC
TCGCCATCGCACGGCCCACTGGCTGATGCGTGAGGCGATCACCCAGTACGTCGAACGCGAAGAGAAGCGAGAAGCCTTTC
GGCAAGATACGCTCAAGGCGTGGGAAGAGTACCGCAGCACTGGACTGCATGTAACGGCCGATGAGGCCGATGCTTGGCTG
GCCGAGCTCGAACAAGGCAATGACATCGAGCCGCCGGAATGTCACGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References