Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3776420..3777060 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag FNU76_RS17230 Protein ID WP_144279333.1
Coordinates 3776647..3777060 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag FNU76_RS17225 Protein ID WP_144280732.1
Coordinates 3776420..3776650 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS17195 3771600..3772559 + 960 WP_144279327.1 ribonuclease Z -
FNU76_RS17200 3772623..3772841 - 219 WP_144279328.1 hypothetical protein -
FNU76_RS17205 3772838..3773269 - 432 WP_144279329.1 VOC family protein -
FNU76_RS17210 3773266..3773742 - 477 WP_144279330.1 helix-turn-helix transcriptional regulator -
FNU76_RS17215 3773867..3774052 + 186 WP_144279331.1 hypothetical protein -
FNU76_RS17220 3774097..3776301 + 2205 WP_144279332.1 OsmC domain/YcaO domain-containing protein -
FNU76_RS17225 3776420..3776650 + 231 WP_144280732.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FNU76_RS17230 3776647..3777060 + 414 WP_144279333.1 type II toxin-antitoxin system VapC family toxin Toxin
FNU76_RS17235 3777057..3778985 - 1929 WP_144279334.1 type IV secretory system conjugative DNA transfer family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-128)

Antitoxin

SpoVT-AbrB domain

(7-50)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15371.66 Da        Isoelectric Point: 6.2225

>T129061 WP_144279333.1 NZ_CP041730:3776647-3777060 [Chitinimonas arctica]
VMTFMLDTCICSYIMRERPESVLQRLANEVSRQNRIVISAITYAEMRFGQIGKKVSPKHAELVDEFVRRIDGILPWDQQA
VDATVVVKQQLAAVGTPIGENDTAIAGHAIASDCVLVTNNFREFNRVQGLTVENWVH

Download         Length: 414 bp

>T129061 NZ_CP041730:3776647-3777060 [Chitinimonas arctica]
GTGATGACGTTCATGCTCGATACCTGTATTTGTTCCTACATCATGCGTGAGCGACCTGAATCGGTCTTGCAGCGTTTGGC
TAACGAAGTGAGTCGCCAAAACCGGATCGTGATTTCGGCCATCACCTATGCCGAAATGCGTTTTGGGCAAATCGGCAAGA
AGGTCTCCCCAAAGCATGCCGAGCTGGTCGATGAATTTGTACGACGTATCGACGGCATCCTTCCCTGGGATCAACAGGCC
GTGGATGCCACGGTAGTCGTCAAACAGCAGCTTGCGGCGGTAGGCACGCCGATAGGGGAGAACGATACCGCTATTGCTGG
GCATGCTATTGCCAGCGATTGCGTCCTGGTAACGAACAATTTTCGTGAATTCAACCGTGTGCAAGGGTTGACAGTCGAAA
ACTGGGTTCACTAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8608.83 Da        Isoelectric Point: 4.7558

>AT129061 WP_144280732.1 NZ_CP041730:3776420-3776650 [Chitinimonas arctica]
MQTVSIFINGKNQAVRLPKNMEFEGVKELEIVKTGDTITLRPVRPSWESFATLPKADEDFLQERTPVVSDEGRFGL

Download         Length: 231 bp

>AT129061 NZ_CP041730:3776420-3776650 [Chitinimonas arctica]
ATGCAAACGGTCTCCATCTTCATAAACGGTAAGAACCAGGCGGTACGCCTGCCAAAGAACATGGAATTCGAAGGCGTTAA
AGAGCTGGAGATTGTCAAAACAGGCGACACCATCACCCTTCGACCGGTCCGACCCAGCTGGGAATCCTTTGCCACCTTGC
CGAAGGCTGATGAGGATTTCTTACAGGAACGTACCCCGGTGGTCAGTGACGAAGGCAGGTTCGGGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References