Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3246622..3247202 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FNU76_RS14645 Protein ID WP_144278887.1
Coordinates 3246622..3247002 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FNU76_RS14650 Protein ID WP_144278888.1
Coordinates 3247005..3247202 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS14615 3241934..3242845 + 912 WP_144278882.1 heme o synthase -
FNU76_RS14620 3242848..3243432 + 585 WP_144278883.1 SCO family protein -
FNU76_RS14625 3243539..3244321 + 783 WP_144278884.1 flagellar brake protein -
FNU76_RS14630 3244332..3245213 - 882 WP_144278885.1 SDR family oxidoreductase -
FNU76_RS14635 3245257..3246282 + 1026 WP_144278886.1 CDP-6-deoxy-delta-3,4-glucoseen reductase -
FNU76_RS14645 3246622..3247002 - 381 WP_144278887.1 VapC toxin family PIN domain ribonuclease Toxin
FNU76_RS14650 3247005..3247202 - 198 WP_144278888.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FNU76_RS14655 3247358..3248245 + 888 WP_144278889.1 hypothetical protein -
FNU76_RS14660 3248296..3248697 - 402 WP_144278890.1 DUF2845 domain-containing protein -
FNU76_RS14665 3248871..3249419 + 549 WP_179958123.1 GNAT family N-acetyltransferase -
FNU76_RS14670 3249465..3252143 - 2679 WP_144278892.1 type VI secretion system ATPase TssH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 14081.62 Da        Isoelectric Point: 6.9682

>T129060 WP_144278887.1 NZ_CP041730:c3247002-3246622 [Chitinimonas arctica]
MRGVLVDTSVWVDHFRLRNDILANLLELDLVMAHPLIVGEVACGTPPNRTQVVSDLAGLQQTHLASIREVVDFIERERLF
GLGCGLVDMMLLASTLMTPGVKLWTLDKRLKALAERFGVMHRPTLH

Download         Length: 381 bp

>T129060 NZ_CP041730:c3247002-3246622 [Chitinimonas arctica]
ATGAGAGGCGTCCTCGTTGATACCTCGGTGTGGGTTGATCATTTTCGGTTACGCAACGATATATTGGCCAACTTGCTTGA
GCTTGACTTGGTGATGGCGCATCCGTTGATTGTTGGCGAGGTCGCCTGTGGAACACCCCCCAATCGGACTCAAGTTGTGT
CGGACCTCGCTGGGCTACAGCAGACCCACCTGGCCAGTATCCGAGAAGTTGTGGACTTTATCGAACGCGAACGCCTTTTC
GGGTTGGGATGTGGCCTGGTAGACATGATGTTGCTTGCATCCACTTTAATGACGCCTGGGGTAAAGTTGTGGACGCTGGA
TAAGCGGCTAAAGGCGTTGGCAGAGCGCTTTGGTGTAATGCACCGCCCCACCTTGCATTGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7380.50 Da        Isoelectric Point: 5.0490

>AT129060 WP_144278888.1 NZ_CP041730:c3247202-3247005 [Chitinimonas arctica]
MRTTVTIDDALYERALEVADPTMDKADLFREAIKTFVRVQAAKRLAALGATMPDMQEIPRRREDA

Download         Length: 198 bp

>AT129060 NZ_CP041730:c3247202-3247005 [Chitinimonas arctica]
ATGAGAACGACTGTCACTATTGACGATGCGCTATATGAAAGGGCCCTGGAAGTTGCCGATCCGACGATGGATAAGGCAGA
TCTGTTCCGCGAGGCCATCAAGACATTTGTGCGAGTTCAAGCAGCCAAGCGTCTTGCCGCCCTTGGCGCAACCATGCCAG
ACATGCAGGAGATTCCTCGCCGTCGTGAGGATGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References