Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 3018074..3018569 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag FNU76_RS13565 Protein ID WP_144278703.1
Coordinates 3018074..3018286 (+) Length 71 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag FNU76_RS13570 Protein ID WP_144278704.1
Coordinates 3018291..3018569 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS13545 3014133..3015068 - 936 WP_144278699.1 DDE-type integrase/transposase/recombinase -
FNU76_RS13550 3015063..3015479 + 417 WP_144278700.1 hypothetical protein -
FNU76_RS13555 3015959..3016435 + 477 WP_144278701.1 helix-turn-helix domain-containing protein -
FNU76_RS13560 3016462..3017781 + 1320 WP_144278702.1 type II toxin-antitoxin system HipA family toxin -
FNU76_RS13565 3018074..3018286 + 213 WP_144278703.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNU76_RS13570 3018291..3018569 + 279 WP_144278704.1 helix-turn-helix domain-containing protein Antitoxin
FNU76_RS13575 3018565..3019017 + 453 WP_144278705.1 RNA 2'-phosphotransferase -
FNU76_RS13580 3019140..3019385 + 246 WP_144278706.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
FNU76_RS13585 3019382..3019768 + 387 WP_144278707.1 type II toxin-antitoxin system VapC family toxin -
FNU76_RS13590 3019827..3020330 - 504 WP_144278708.1 DoxX family protein -
FNU76_RS13595 3020342..3021121 - 780 WP_144278709.1 putative DNA-binding domain-containing protein -
FNU76_RS13600 3021118..3021948 - 831 WP_144278710.1 DUF692 domain-containing protein -
FNU76_RS13605 3022021..3022290 - 270 WP_144278711.1 DUF2282 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-62)

Antitoxin

HigA2-like, helix-turn-helix domain

(20-92)


Sequences

Toxin        


Download         Length: 71 a.a.        Molecular weight: 7853.07 Da        Isoelectric Point: 9.7547

>T129059 WP_144278703.1 NZ_CP041730:3018074-3018286 [Chitinimonas arctica]
MNSNKSFVLAQNQAPLIDYDYRAVYTVRYATAVYVLHCFQKKSTSGIATPKPDMELIEARLKAVAAREKG

Download         Length: 213 bp

>T129059 NZ_CP041730:3018074-3018286 [Chitinimonas arctica]
ATGAACAGCAACAAGAGCTTCGTGCTGGCCCAGAACCAGGCCCCCCTGATCGACTACGACTACCGTGCCGTTTATACGGT
GCGCTATGCGACGGCGGTGTATGTACTGCATTGCTTTCAGAAGAAATCGACCAGTGGTATCGCTACACCCAAGCCGGATA
TGGAGTTGATCGAAGCTCGTTTGAAAGCGGTTGCGGCACGGGAAAAGGGGTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10415.04 Da        Isoelectric Point: 4.6899

>AT129059 WP_144278704.1 NZ_CP041730:3018291-3018569 [Chitinimonas arctica]
MNELEIIDDISIEQGSDNPYADLDRPDADEMLIKAELAREIAQIIKSRHLTQLRAAELLGMPHPKLSEMLRGKFRGISQA
KMIECLNRLGLD

Download         Length: 279 bp

>AT129059 NZ_CP041730:3018291-3018569 [Chitinimonas arctica]
ATGAACGAGTTAGAAATCATCGACGACATCAGCATCGAGCAGGGCAGCGATAACCCCTACGCCGATCTAGACCGACCTGA
CGCCGACGAAATGCTGATTAAGGCCGAACTGGCACGCGAGATCGCCCAGATCATCAAAAGCCGGCACCTGACTCAACTGC
GGGCGGCCGAACTGTTGGGCATGCCGCATCCGAAGCTCTCCGAAATGCTGCGTGGCAAGTTCCGTGGTATCAGTCAGGCC
AAGATGATCGAATGTTTGAACAGGCTGGGCCTCGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References