Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 2143294..2143955 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FNU76_RS09785 Protein ID WP_144278024.1
Coordinates 2143542..2143955 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FNU76_RS09780 Protein ID WP_144278023.1
Coordinates 2143294..2143545 (+) Length 84 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS09755 2138722..2139984 - 1263 WP_144278019.1 hypothetical protein -
FNU76_RS09760 2139991..2141115 - 1125 WP_144278020.1 GTPase ObgE -
FNU76_RS09765 2141275..2141547 - 273 WP_144278021.1 50S ribosomal protein L27 -
FNU76_RS09770 2141563..2141874 - 312 WP_144280626.1 50S ribosomal protein L21 -
FNU76_RS09775 2142167..2143135 + 969 WP_144278022.1 polyprenyl synthetase family protein -
FNU76_RS09780 2143294..2143545 + 252 WP_144278023.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FNU76_RS09785 2143542..2143955 + 414 WP_144278024.1 type II toxin-antitoxin system VapC family toxin Toxin
FNU76_RS09790 2144307..2145335 + 1029 WP_144278025.1 hypothetical protein -
FNU76_RS09795 2145425..2147173 - 1749 WP_144278026.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-122)

Antitoxin

(1-72)


Sequences


Toxin        


Download         Length: 138 a.a.        Molecular weight: 15451.81 Da        Isoelectric Point: 8.4627

>T129058 WP_144278024.1 NZ_CP041730:2143542-2143955 [Chitinimonas arctica]
MSYLVDTNVLSELRNRKADANVLAWMQARPRQSLYLSVLSLGEIRKGIEGVADPAFRQTLMDWLEVDLPNYFVGRLLNID
QQVADRWGRVQAKAGRTLPVIDGLLAATALHYDLTLVTRNTKDFVGLGVTLVNPWER

Download         Length: 414 bp

>T129058 NZ_CP041730:2143542-2143955 [Chitinimonas arctica]
TTGAGCTATTTGGTCGATACCAATGTCTTGTCGGAGTTGCGAAACAGGAAAGCCGACGCAAATGTCCTGGCCTGGATGCA
GGCACGCCCGCGCCAGTCGCTCTATCTCTCCGTATTGAGCCTGGGAGAAATCCGGAAGGGTATCGAAGGGGTCGCCGATC
CAGCGTTCCGCCAGACGCTAATGGACTGGTTGGAAGTGGATCTGCCTAATTACTTTGTTGGCAGGCTGCTGAACATAGAC
CAGCAAGTCGCAGACCGCTGGGGGCGCGTGCAGGCAAAAGCGGGACGTACATTGCCCGTCATTGATGGCCTGCTGGCGGC
AACGGCCCTGCACTACGATCTGACGCTGGTGACGAGAAATACCAAGGACTTCGTGGGTCTTGGGGTGACGCTCGTCAACC
CTTGGGAGAGGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9370.56 Da        Isoelectric Point: 4.7616

>AT129058 WP_144278023.1 NZ_CP041730:2143294-2143545 [Chitinimonas arctica]
MQSWQMQTAKARFSELVKHAAQEGPQDITLHGQSIAVVVSRELFDRLSGNEQTLVEFMRASPLAGQDEIEFERNPGLPRE
IAF

Download         Length: 252 bp

>AT129058 NZ_CP041730:2143294-2143545 [Chitinimonas arctica]
ATGCAAAGCTGGCAAATGCAAACCGCCAAGGCTCGGTTTTCGGAATTGGTCAAACACGCGGCCCAGGAGGGGCCGCAGGA
CATCACGCTGCACGGTCAGTCCATAGCGGTAGTGGTGTCACGCGAGTTGTTCGACCGCTTGTCCGGCAATGAGCAGACCT
TGGTGGAGTTCATGCGCGCCTCGCCACTGGCGGGGCAGGATGAAATCGAGTTCGAACGCAATCCAGGCTTGCCGCGTGAG
ATCGCGTTTTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References