Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1118119..1118596 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag FNU76_RS04875 Protein ID WP_143856660.1
Coordinates 1118119..1118388 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag FNU76_RS04880 Protein ID WP_144280585.1
Coordinates 1118372..1118596 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS04865 1116340..1116825 + 486 WP_143856659.1 hypothetical protein -
FNU76_RS04870 1117226..1118083 + 858 WP_144280584.1 transposase -
FNU76_RS04875 1118119..1118388 - 270 WP_143856660.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNU76_RS04880 1118372..1118596 - 225 WP_144280585.1 TraY domain-containing protein Antitoxin
FNU76_RS04885 1119069..1119359 + 291 WP_143856661.1 helix-turn-helix domain-containing protein -
FNU76_RS04890 1119480..1119641 + 162 WP_143856662.1 DNA-binding protein -
FNU76_RS04895 1119638..1120003 + 366 WP_143856663.1 hypothetical protein -
FNU76_RS04900 1120165..1120833 - 669 WP_143856664.1 site-2 protease family protein -
FNU76_RS04905 1120979..1121665 - 687 WP_143856665.1 site-2 protease family protein -
FNU76_RS04910 1121704..1122228 - 525 WP_143856666.1 CPBP family intramembrane metalloprotease -
FNU76_RS04915 1122225..1122848 - 624 WP_143856667.1 threonylcarbamoyl-AMP synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Protein of unknown function DUF6290

(3-70)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10254.88 Da        Isoelectric Point: 9.9850

>T129056 WP_143856660.1 NZ_CP041730:c1118388-1118119 [Chitinimonas arctica]
MAWRIEVTDSALKQLGKLDRPVAQRIRSFLLDRLATLDDPRSIGEALKGGELGELWKYRVGDYRIISSIEDGALKILVVR
IDNRREVYR

Download         Length: 270 bp

>T129056 NZ_CP041730:c1118388-1118119 [Chitinimonas arctica]
TTGGCCTGGCGGATTGAAGTGACCGATAGCGCCCTGAAACAGCTTGGCAAGCTGGATCGGCCGGTTGCCCAGCGTATCCG
CAGCTTCCTGCTGGATCGATTGGCGACCTTGGATGACCCGCGCTCAATCGGTGAAGCGCTCAAAGGCGGTGAACTGGGCG
AGCTCTGGAAGTACCGGGTAGGTGATTACCGCATCATCAGCAGCATCGAGGATGGTGCGTTGAAAATTCTGGTGGTGCGG
ATTGACAACCGGCGCGAGGTGTATCGCTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8606.77 Da        Isoelectric Point: 4.5052

>AT129056 WP_144280585.1 NZ_CP041730:c1118596-1118372 [Chitinimonas arctica]
MLAIRLPQDIETRLENLAQRTGRTKSFYVREAIMEHLEDLEDLYLAEQVLRRVRSGEEQTYTLAEVEAKLGLAD

Download         Length: 225 bp

>AT129056 NZ_CP041730:c1118596-1118372 [Chitinimonas arctica]
ATGCTGGCCATCCGTCTCCCGCAAGACATCGAGACCCGCCTGGAAAATCTGGCGCAGCGCACTGGGCGCACCAAGAGCTT
CTATGTTCGCGAAGCGATCATGGAGCACTTGGAAGACCTGGAAGACCTCTACCTGGCCGAGCAGGTACTGCGGCGCGTGC
GCAGTGGCGAGGAGCAGACTTACACCCTGGCAGAAGTAGAGGCAAAGCTTGGCCTGGCGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References