Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1060562..1061172 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FNU76_RS04715 Protein ID WP_143856634.1
Coordinates 1060562..1060852 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FNU76_RS04720 Protein ID WP_143856635.1
Coordinates 1060864..1061172 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS04695 1056446..1058053 + 1608 WP_143856630.1 diguanylate cyclase -
FNU76_RS04700 1058060..1058845 - 786 WP_143856631.1 MOSC domain-containing protein -
FNU76_RS04705 1058963..1059823 + 861 WP_143856632.1 DMT family transporter -
FNU76_RS04710 1059891..1060253 - 363 WP_143856633.1 hypothetical protein -
FNU76_RS04715 1060562..1060852 + 291 WP_143856634.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNU76_RS04720 1060864..1061172 + 309 WP_143856635.1 putative addiction module antidote protein Antitoxin
FNU76_RS04725 1061331..1062866 + 1536 WP_143856636.1 N-acylglucosamine 2-epimerase -
FNU76_RS24050 1063079..1063333 + 255 WP_179958351.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1059891..1084860 24969


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(6-98)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10795.47 Da        Isoelectric Point: 10.3350

>T129055 WP_143856634.1 NZ_CP041730:1060562-1060852 [Chitinimonas arctica]
MLKISKTSVYEMWFQGLRDKTVKARINARLSRLSLGNHGDAKPVGHGVSELRIDYGPGYRVYYFQTGVELIILLAGGDKS
TQARDIQTALQLRKDL

Download         Length: 291 bp

>T129055 NZ_CP041730:1060562-1060852 [Chitinimonas arctica]
ATGCTAAAAATAAGCAAAACTAGCGTATACGAAATGTGGTTTCAAGGTTTACGTGATAAAACAGTGAAGGCACGTATCAA
TGCGCGCTTATCCAGACTGTCACTAGGTAACCACGGAGATGCCAAACCCGTTGGGCATGGCGTGTCCGAATTACGCATTG
ATTACGGACCAGGCTATAGGGTGTATTACTTTCAGACAGGAGTCGAATTGATCATTCTACTAGCTGGCGGTGACAAATCC
ACCCAGGCAAGAGATATACAAACTGCATTGCAATTGCGTAAAGACCTATGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10685.16 Da        Isoelectric Point: 4.7683

>AT129055 WP_143856635.1 NZ_CP041730:1060864-1061172 [Chitinimonas arctica]
MKPVITDWDAADYLATREDQALYLDACIAEADGDAALIAKALGDIARARGMAQVAAASGLSRESLYKGLSIDGNPSFSTV
LRVMKTLGLELHASAKKEATSA

Download         Length: 309 bp

>AT129055 NZ_CP041730:1060864-1061172 [Chitinimonas arctica]
ATGAAACCCGTAATTACCGATTGGGATGCGGCAGACTATCTCGCCACACGAGAAGACCAAGCCCTATACCTGGATGCCTG
TATCGCAGAGGCCGATGGCGATGCGGCCCTTATTGCCAAGGCGCTAGGGGACATTGCGCGCGCGCGCGGCATGGCGCAAG
TAGCCGCTGCGTCTGGATTATCACGCGAAAGTCTATACAAGGGGCTATCCATTGATGGCAATCCTTCATTTTCCACAGTT
TTAAGAGTTATGAAGACTCTCGGCTTGGAGCTGCATGCCAGCGCCAAGAAAGAGGCTACCTCAGCCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References