Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 850725..851392 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FNU76_RS03700 Protein ID WP_143856454.1
Coordinates 850725..851141 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FNU76_RS03705 Protein ID WP_143856455.1
Coordinates 851138..851392 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS03685 846043..849324 + 3282 WP_143856451.1 S41 family peptidase -
FNU76_RS03690 849345..849914 + 570 WP_143856452.1 DNA-3-methyladenine glycosylase I -
FNU76_RS03695 849954..850631 + 678 WP_143856453.1 alpha/beta hydrolase -
FNU76_RS03700 850725..851141 - 417 WP_143856454.1 type II toxin-antitoxin system VapC family toxin Toxin
FNU76_RS03705 851138..851392 - 255 WP_143856455.1 plasmid stabilization protein Antitoxin
FNU76_RS03710 851602..853320 - 1719 WP_143856456.1 hypothetical protein -
FNU76_RS03715 853320..853682 - 363 WP_143856457.1 STAS/SEC14 domain-containing protein -
FNU76_RS03720 853734..854129 - 396 WP_143856458.1 holo-ACP synthase -
FNU76_RS03725 854131..854874 - 744 WP_143856459.1 DNA repair protein RecO -
FNU76_RS03730 854906..855802 - 897 WP_143856460.1 GTPase Era -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14803.97 Da        Isoelectric Point: 6.2268

>T129054 WP_143856454.1 NZ_CP041730:c851141-850725 [Chitinimonas arctica]
MIVLDTNVVSEAMKPEPHPAVRAWLNDQAAETLYLSSVTQAELLFGIAALPAGRRKDSLARTLDGLMGLFGERVLPFDTH
AARHYAELAVNAKAGGRGFPIPDGYIAAIAASRRFIVASRDMAPYEAAGVSVINPWEA

Download         Length: 417 bp

>T129054 NZ_CP041730:c851141-850725 [Chitinimonas arctica]
ATGATCGTCCTCGATACCAACGTCGTTTCAGAGGCGATGAAACCCGAGCCGCATCCAGCCGTGCGGGCTTGGCTGAACGA
TCAAGCTGCCGAAACGTTATATCTGTCCAGTGTGACTCAGGCCGAATTACTGTTTGGCATCGCTGCACTCCCAGCTGGTA
GGCGAAAGGATAGTCTGGCACGGACCCTTGATGGCCTGATGGGCCTATTCGGCGAGCGGGTGCTGCCCTTCGATACCCAT
GCGGCACGGCACTATGCCGAGCTTGCAGTGAACGCCAAGGCTGGCGGACGAGGATTCCCAATACCTGACGGCTACATCGC
TGCGATTGCCGCGTCGCGGCGTTTCATCGTGGCGTCGCGCGATATGGCCCCTTACGAGGCCGCCGGCGTTTCCGTCATCA
ATCCGTGGGAAGCATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9541.87 Da        Isoelectric Point: 6.4732

>AT129054 WP_143856455.1 NZ_CP041730:c851392-851138 [Chitinimonas arctica]
MAMLTVRNLPDDVHRALRVRAAQHGRSTEAEVREILAMAVKPEERVRMGDALAALGRQNGLSNEDFEIFDRVKDRTPAEP
LRFE

Download         Length: 255 bp

>AT129054 NZ_CP041730:c851392-851138 [Chitinimonas arctica]
ATGGCAATGCTGACCGTACGCAATCTGCCTGACGATGTGCATCGCGCTTTACGGGTACGGGCAGCGCAACATGGGCGCAG
TACCGAGGCTGAGGTCCGAGAAATTCTGGCGATGGCGGTCAAGCCGGAAGAGCGTGTTCGCATGGGTGATGCCCTGGCGG
CATTGGGCCGCCAGAACGGCCTGAGCAACGAGGATTTCGAGATCTTCGACCGAGTAAAAGATAGAACGCCGGCCGAGCCG
CTGAGATTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References