Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 633312..634018 Replicon chromosome
Accession NZ_CP041730
Organism Chitinimonas arctica strain R3-44

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FNU76_RS02955 Protein ID WP_143856321.1
Coordinates 633569..634018 (+) Length 150 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FNU76_RS02950 Protein ID WP_143856320.1
Coordinates 633312..633572 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNU76_RS02930 628465..629262 + 798 WP_143856317.1 carbohydrate ABC transporter permease -
FNU76_RS02935 629510..629773 + 264 WP_143856318.1 DUF2160 domain-containing protein -
FNU76_RS02940 629908..631584 + 1677 WP_144280560.1 ABC transporter substrate-binding protein -
FNU76_RS02945 631652..633139 + 1488 WP_143856319.1 glycerol kinase GlpK -
FNU76_RS02950 633312..633572 + 261 WP_143856320.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FNU76_RS02955 633569..634018 + 450 WP_143856321.1 type II toxin-antitoxin system VapC family toxin Toxin
FNU76_RS02960 634191..634607 + 417 WP_143856322.1 DNA topoisomerase IB -
FNU76_RS02965 634651..634875 + 225 WP_143856323.1 hypothetical protein -
FNU76_RS02970 634944..635714 + 771 WP_143856324.1 triose-phosphate isomerase -
FNU76_RS02975 635892..638210 + 2319 WP_143856325.1 PBP1A family penicillin-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-132)

Antitoxin

SpoVT-AbrB domain

(8-54)


Sequences

Toxin        


Download         Length: 150 a.a.        Molecular weight: 15935.74 Da        Isoelectric Point: 7.9497

>T129053 WP_143856321.1 NZ_CP041730:633569-634018 [Chitinimonas arctica]
MTTYLLDTNIASHIIKGDIPRVRERLVAVPIHCVAVSVVTQAELLYGVAKRGHPLGLTTKVHEFLAHVPVLPWTAKVAEV
YGELRIACEAGGVTLAPMDMMIAAHAKTLALAASQALGQAILVTRDGAFSRARMLGGLTLEDWTKEVAS

Download         Length: 450 bp

>T129053 NZ_CP041730:633569-634018 [Chitinimonas arctica]
ATGACGACATATCTGCTCGACACCAACATTGCAAGCCACATCATCAAGGGCGACATCCCACGCGTGCGGGAGCGCCTTGT
TGCGGTACCGATTCATTGCGTCGCGGTCTCGGTCGTGACGCAAGCCGAACTGCTGTACGGCGTCGCCAAGCGCGGCCATC
CTCTGGGGCTCACGACCAAGGTTCACGAGTTCCTGGCGCACGTGCCGGTCTTGCCTTGGACGGCCAAGGTGGCTGAAGTC
TACGGTGAGCTACGCATAGCCTGTGAGGCAGGTGGTGTGACGCTCGCGCCAATGGACATGATGATTGCCGCGCATGCGAA
GACCCTAGCGCTGGCCGCATCGCAGGCACTGGGCCAGGCGATCTTGGTTACGAGGGATGGCGCGTTCTCACGAGCGCGCA
TGCTCGGTGGATTGACGCTCGAAGACTGGACAAAAGAAGTGGCATCCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9854.88 Da        Isoelectric Point: 4.3603

>AT129053 WP_143856320.1 NZ_CP041730:633312-633572 [Chitinimonas arctica]
MTQTAKIFTTGRSQAVRLPLEFRFDEKEVYIRRDVVTGDVILSRRPDSWDGFFALDATTDVPADFMSEADRNQGEHSRDP
FDDTPV

Download         Length: 261 bp

>AT129053 NZ_CP041730:633312-633572 [Chitinimonas arctica]
ATGACACAGACCGCCAAAATCTTCACCACGGGCCGCAGCCAGGCAGTTCGCTTGCCGCTCGAATTCCGTTTCGACGAGAA
GGAGGTCTACATCCGCCGGGATGTGGTCACGGGCGACGTGATCCTGTCACGCCGGCCAGATTCGTGGGATGGCTTCTTCG
CCCTTGATGCGACAACGGACGTTCCGGCCGACTTCATGAGCGAGGCTGATCGCAATCAGGGCGAGCACTCCCGCGACCCG
TTCGACGACACACCGGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References