Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ParST/RES-TIGR02293 |
| Location | 92296..93356 | Replicon | plasmid unnamed3 |
| Accession | NZ_CP041719 | ||
| Organism | Acidiphilium multivorum strain JZ-6 | ||
Toxin (Protein)
| Gene name | ParT | Uniprot ID | - |
| Locus tag | FE249_RS20025 | Protein ID | WP_241420037.1 |
| Coordinates | 92296..92784 (-) | Length | 163 a.a. |
Antitoxin (Protein)
| Gene name | ParS | Uniprot ID | - |
| Locus tag | FE249_RS20030 | Protein ID | WP_241420038.1 |
| Coordinates | 92781..93356 (-) | Length | 192 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FE249_RS20005 (FE249_19880) | 87449..88681 | - | 1233 | WP_241420033.1 | serine hydrolase domain-containing protein | - |
| FE249_RS20010 (FE249_19885) | 88950..90065 | - | 1116 | WP_241420034.1 | hypothetical protein | - |
| FE249_RS20015 (FE249_19890) | 90151..90942 | + | 792 | WP_241420035.1 | hypothetical protein | - |
| FE249_RS20020 (FE249_19895) | 91154..92281 | + | 1128 | WP_241420036.1 | site-specific integrase | - |
| FE249_RS20025 (FE249_19900) | 92296..92784 | - | 489 | WP_241420037.1 | RES family NAD+ phosphorylase | Toxin |
| FE249_RS20030 (FE249_19905) | 92781..93356 | - | 576 | WP_241420038.1 | DUF2384 domain-containing protein | Antitoxin |
| FE249_RS20035 (FE249_19910) | 93507..93971 | + | 465 | WP_241420039.1 | hypothetical protein | - |
| FE249_RS20040 (FE249_19915) | 94122..94739 | + | 618 | WP_241420040.1 | ATP-binding protein | - |
| FE249_RS20045 (FE249_19920) | 95398..96060 | + | 663 | WP_011930611.1 | ParA family protein | - |
| FE249_RS20050 (FE249_19925) | 96888..97823 | + | 936 | WP_241420041.1 | replication protein RepA | - |
| FE249_RS20055 | 98145..98282 | + | 138 | WP_174501999.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..140889 | 140889 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 163 a.a. Molecular weight: 18033.54 Da Isoelectric Point: 7.3570
>T129029 WP_241420037.1 NZ_CP041719:c92784-92296 [Acidiphilium multivorum]
VTASFWRIGTDTRDYTADDRSGKGAEITGGRWNDVGTPMVYAASSRALACLETVVHLNGSGLPLNRYLVEIIIPDDLVRS
AETYDEASLPVGWDAEPPGKVSIDLGTTWVRDKRSAVLFVPSVIVPEELNVLINPTHPGARKIQFHKRRKWLYDPRILAL
RH
VTASFWRIGTDTRDYTADDRSGKGAEITGGRWNDVGTPMVYAASSRALACLETVVHLNGSGLPLNRYLVEIIIPDDLVRS
AETYDEASLPVGWDAEPPGKVSIDLGTTWVRDKRSAVLFVPSVIVPEELNVLINPTHPGARKIQFHKRRKWLYDPRILAL
RH
Download Length: 489 bp
>T129029 NZ_CP041719:c92784-92296 [Acidiphilium multivorum]
GTGACCGCGAGTTTCTGGAGGATCGGGACAGACACTCGGGATTATACGGCGGACGACAGGAGCGGAAAGGGAGCGGAGAT
CACGGGCGGACGCTGGAATGACGTTGGCACCCCAATGGTTTACGCAGCATCCTCACGCGCGCTGGCTTGCCTCGAAACTG
TGGTGCATCTGAACGGGAGCGGTTTGCCGCTGAACCGATATCTGGTCGAGATCATCATCCCGGATGATCTGGTCAGATCG
GCAGAGACATATGATGAGGCATCGCTGCCTGTGGGGTGGGATGCGGAGCCTCCCGGGAAGGTGAGTATCGACTTGGGAAC
CACTTGGGTCCGGGACAAAAGATCGGCGGTATTATTCGTCCCATCCGTTATCGTTCCCGAGGAGCTGAACGTCCTCATCA
ACCCGACCCATCCAGGTGCCCGCAAAATACAGTTTCACAAGCGCCGGAAATGGCTGTACGACCCGCGCATACTTGCGCTG
CGGCATTGA
GTGACCGCGAGTTTCTGGAGGATCGGGACAGACACTCGGGATTATACGGCGGACGACAGGAGCGGAAAGGGAGCGGAGAT
CACGGGCGGACGCTGGAATGACGTTGGCACCCCAATGGTTTACGCAGCATCCTCACGCGCGCTGGCTTGCCTCGAAACTG
TGGTGCATCTGAACGGGAGCGGTTTGCCGCTGAACCGATATCTGGTCGAGATCATCATCCCGGATGATCTGGTCAGATCG
GCAGAGACATATGATGAGGCATCGCTGCCTGTGGGGTGGGATGCGGAGCCTCCCGGGAAGGTGAGTATCGACTTGGGAAC
CACTTGGGTCCGGGACAAAAGATCGGCGGTATTATTCGTCCCATCCGTTATCGTTCCCGAGGAGCTGAACGTCCTCATCA
ACCCGACCCATCCAGGTGCCCGCAAAATACAGTTTCACAAGCGCCGGAAATGGCTGTACGACCCGCGCATACTTGCGCTG
CGGCATTGA
Antitoxin
Download Length: 192 a.a. Molecular weight: 20444.73 Da Isoelectric Point: 10.7092
>AT129029 WP_241420038.1 NZ_CP041719:c93356-92781 [Acidiphilium multivorum]
MVTTTVSKAATRTPSGAKANKPSHKAPKTSRALKVPMTSPGSPAAKGGTDVPYLEYFCQAPMRQIEMIRRGIPALTVKRI
AGDLRIEQDTLLRALNLSVATLNRKVAQAKNLPADESERIAGIARLVGQVEAMVKESGDPEGFNAAEWLSRWLREPLPAL
GGQMPIKLLDTMAGQALVSQALSRIQSGAYA
MVTTTVSKAATRTPSGAKANKPSHKAPKTSRALKVPMTSPGSPAAKGGTDVPYLEYFCQAPMRQIEMIRRGIPALTVKRI
AGDLRIEQDTLLRALNLSVATLNRKVAQAKNLPADESERIAGIARLVGQVEAMVKESGDPEGFNAAEWLSRWLREPLPAL
GGQMPIKLLDTMAGQALVSQALSRIQSGAYA
Download Length: 576 bp
>AT129029 NZ_CP041719:c93356-92781 [Acidiphilium multivorum]
ATGGTTACCACGACTGTGAGCAAAGCCGCGACCAGAACACCTTCAGGTGCGAAGGCAAACAAGCCTTCGCACAAGGCCCC
CAAGACATCTCGCGCGCTTAAGGTTCCCATGACATCTCCCGGATCCCCGGCGGCAAAAGGTGGGACCGATGTGCCCTACC
TGGAATACTTTTGTCAGGCGCCTATGCGCCAAATCGAGATGATCAGGAGGGGGATTCCCGCGCTCACCGTAAAGCGGATC
GCAGGTGATCTCAGGATCGAGCAGGACACATTGCTCCGTGCGCTCAACCTGAGTGTAGCCACCCTGAATCGTAAGGTCGC
CCAGGCGAAGAATCTGCCGGCCGATGAGAGCGAGCGCATTGCCGGTATTGCGCGACTGGTGGGGCAGGTCGAGGCTATGG
TGAAGGAATCCGGTGATCCAGAGGGATTTAACGCCGCAGAATGGCTCTCGCGCTGGTTGCGCGAGCCATTGCCAGCGCTC
GGCGGTCAGATGCCTATCAAATTGCTTGACACGATGGCGGGGCAAGCCCTCGTCTCACAGGCATTGTCCCGCATTCAGAG
CGGGGCCTATGCGTGA
ATGGTTACCACGACTGTGAGCAAAGCCGCGACCAGAACACCTTCAGGTGCGAAGGCAAACAAGCCTTCGCACAAGGCCCC
CAAGACATCTCGCGCGCTTAAGGTTCCCATGACATCTCCCGGATCCCCGGCGGCAAAAGGTGGGACCGATGTGCCCTACC
TGGAATACTTTTGTCAGGCGCCTATGCGCCAAATCGAGATGATCAGGAGGGGGATTCCCGCGCTCACCGTAAAGCGGATC
GCAGGTGATCTCAGGATCGAGCAGGACACATTGCTCCGTGCGCTCAACCTGAGTGTAGCCACCCTGAATCGTAAGGTCGC
CCAGGCGAAGAATCTGCCGGCCGATGAGAGCGAGCGCATTGCCGGTATTGCGCGACTGGTGGGGCAGGTCGAGGCTATGG
TGAAGGAATCCGGTGATCCAGAGGGATTTAACGCCGCAGAATGGCTCTCGCGCTGGTTGCGCGAGCCATTGCCAGCGCTC
GGCGGTCAGATGCCTATCAAATTGCTTGACACGATGGCGGGGCAAGCCCTCGTCTCACAGGCATTGTCCCGCATTCAGAG
CGGGGCCTATGCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|