Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4783907..4784427 Replicon chromosome
Accession NZ_CP041692
Organism Microlunatus sp. KUDC0627

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FOE78_RS21855 Protein ID WP_143988134.1
Coordinates 4783907..4784197 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FOE78_RS21860 Protein ID WP_143988135.1
Coordinates 4784194..4784427 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOE78_RS21825 4778911..4779636 - 726 WP_143988129.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase -
FOE78_RS21830 4779770..4780255 - 486 WP_091523288.1 CarD family transcriptional regulator -
FOE78_RS21835 4780583..4781206 + 624 WP_143988130.1 hypothetical protein -
FOE78_RS21840 4781221..4782195 - 975 WP_143988131.1 ribose-phosphate pyrophosphokinase -
FOE78_RS21845 4782243..4782707 - 465 WP_143988132.1 pyridoxamine 5'-phosphate oxidase family protein -
FOE78_RS21850 4782788..4783567 + 780 WP_168207627.1 phosphotransferase -
FOE78_RS21855 4783907..4784197 - 291 WP_143988134.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOE78_RS21860 4784194..4784427 - 234 WP_143988135.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
FOE78_RS21865 4784617..4785294 - 678 WP_143988136.1 response regulator transcription factor -
FOE78_RS21870 4785291..4786631 - 1341 WP_210414709.1 two-component sensor histidine kinase -
FOE78_RS21875 4786830..4787495 + 666 WP_143988137.1 phosphate signaling complex protein PhoU -
FOE78_RS21880 4787517..4788266 - 750 WP_143988138.1 phosphoglyceromutase -
FOE78_RS21885 4788360..4789124 + 765 WP_143988139.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11197.52 Da        Isoelectric Point: 6.2224

>T129011 WP_143988134.1 NZ_CP041692:c4784197-4783907 [Microlunatus sp. KUDC0627]
MRSYRLTPAAVQDLSSIWDYTVERWDGGQAETYVNEIRAAVERLAESPDRGRACDEIREGYRRYGIGSHIIFYVVNQDSV
DVVRILHQRMDPTRHL

Download         Length: 291 bp

>T129011 NZ_CP041692:c4784197-4783907 [Microlunatus sp. KUDC0627]
ATGAGGAGCTACCGGCTCACTCCGGCCGCCGTCCAGGACCTCTCGTCCATCTGGGACTACACGGTAGAGCGGTGGGATGG
CGGTCAGGCCGAGACCTATGTCAACGAGATTAGGGCCGCGGTCGAGCGCCTCGCCGAGAGCCCCGACCGCGGCCGTGCCT
GCGACGAGATCCGCGAAGGCTACCGCCGGTACGGGATCGGCAGCCACATCATCTTCTACGTCGTGAACCAAGACAGTGTG
GACGTGGTCCGCATCCTGCACCAGCGGATGGACCCGACCCGGCACCTGTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8317.31 Da        Isoelectric Point: 4.7318

>AT129011 WP_143988135.1 NZ_CP041692:c4784427-4784194 [Microlunatus sp. KUDC0627]
MSLNTSISLDEHFADFLAHEVATGRYRSASEVVRAALRLLEDQESQMAALRAALVSGEESGGAKPFDFDAFITAKKA

Download         Length: 234 bp

>AT129011 NZ_CP041692:c4784427-4784194 [Microlunatus sp. KUDC0627]
ATGAGCTTGAACACGTCGATCAGTCTGGACGAGCATTTCGCGGATTTCCTCGCCCACGAGGTCGCGACGGGGCGCTACCG
ATCGGCGAGCGAGGTGGTACGCGCGGCATTGCGTTTGCTGGAGGACCAGGAGTCCCAAATGGCTGCACTGCGCGCCGCGC
TGGTGTCCGGGGAGGAGAGCGGCGGGGCGAAGCCATTCGACTTCGATGCGTTCATCACGGCGAAGAAGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References