Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 4570073..4570776 Replicon chromosome
Accession NZ_CP041692
Organism Microlunatus sp. KUDC0627

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FOE78_RS20840 Protein ID WP_168207617.1
Coordinates 4570336..4570776 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FOE78_RS20835 Protein ID WP_143987964.1
Coordinates 4570073..4570339 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOE78_RS20810 4566743..4567636 + 894 WP_143987959.1 carboxylating nicotinate-nucleotide diphosphorylase -
FOE78_RS20815 4567690..4567956 + 267 WP_143987960.1 prevent-host-death protein -
FOE78_RS20820 4567946..4568401 + 456 WP_143987961.1 type II toxin-antitoxin system VapC family toxin -
FOE78_RS20825 4568383..4569051 - 669 WP_143987962.1 helix-turn-helix transcriptional regulator -
FOE78_RS20830 4569188..4570012 + 825 WP_143987963.1 class I SAM-dependent methyltransferase -
FOE78_RS20835 4570073..4570339 + 267 WP_143987964.1 antitoxin Antitoxin
FOE78_RS20840 4570336..4570776 + 441 WP_168207617.1 PIN domain-containing protein Toxin
FOE78_RS20845 4570787..4574053 - 3267 WP_143987966.1 isoleucine--tRNA ligase -
FOE78_RS20850 4574315..4574965 - 651 WP_143987967.1 TetR/AcrR family transcriptional regulator C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(5-142)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 16361.45 Da        Isoelectric Point: 4.5428

>T129009 WP_168207617.1 NZ_CP041692:4570336-4570776 [Microlunatus sp. KUDC0627]
VSSYVPDTNVWLALTVAVHGKHLACRDWIQSIGDTDSIAFCRATRQSLLRLLTTAAVLKPYDLPPLSNEQAWATYDLFTS
DSRISLAEEPAEIDQDWRIRSSRPDPSPKLWMDSYLAAFAKATAATFVTTDQAFRQWADLEVAIID

Download         Length: 441 bp

>T129009 NZ_CP041692:4570336-4570776 [Microlunatus sp. KUDC0627]
GTGAGCTCGTATGTGCCGGACACGAACGTTTGGCTGGCGCTGACAGTAGCTGTGCACGGCAAGCACCTTGCTTGCCGTGA
CTGGATTCAAAGCATCGGCGACACCGATTCGATCGCGTTCTGTCGAGCGACCCGCCAGTCCCTGCTGCGACTGCTGACGA
CGGCAGCTGTCCTCAAGCCGTACGATCTGCCACCGCTGTCCAACGAGCAGGCATGGGCAACGTACGACCTGTTCACGTCG
GATAGCCGAATCTCTCTCGCTGAGGAGCCGGCGGAGATTGATCAGGACTGGCGGATCCGATCCTCTCGTCCCGATCCGTC
GCCGAAGCTTTGGATGGACAGTTACCTAGCGGCATTCGCAAAGGCTACGGCGGCGACCTTCGTGACGACCGACCAAGCCT
TCCGTCAGTGGGCCGATCTGGAAGTCGCCATCATCGACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9684.07 Da        Isoelectric Point: 5.1751

>AT129009 WP_143987964.1 NZ_CP041692:4570073-4570339 [Microlunatus sp. KUDC0627]
MKTTLDLPDDLMRTVKVRAAQEDRRLKDVIADLLRRGLAAESAPRQGAAQRVQFPIIAGGHPAKPEEEVTPERVAELLLN
DEVDSVGK

Download         Length: 267 bp

>AT129009 NZ_CP041692:4570073-4570339 [Microlunatus sp. KUDC0627]
ATGAAGACGACTCTGGATCTGCCAGACGATCTGATGCGAACCGTCAAGGTGCGGGCGGCCCAGGAGGATCGGCGGCTGAA
GGACGTAATCGCCGATCTCTTGCGCCGGGGCCTGGCTGCAGAGTCAGCACCACGACAGGGCGCAGCACAGCGCGTGCAAT
TCCCGATCATTGCCGGCGGTCACCCGGCGAAACCTGAAGAGGAAGTCACTCCGGAGAGAGTTGCCGAATTGCTGCTCAAC
GACGAAGTGGATTCGGTGGGCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References