Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 3244074..3244627 Replicon chromosome
Accession NZ_CP041692
Organism Microlunatus sp. KUDC0627

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FOE78_RS14500 Protein ID WP_143986929.1
Coordinates 3244355..3244627 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FOE78_RS14495 Protein ID WP_210414593.1
Coordinates 3244074..3244358 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOE78_RS14470 3240675..3241103 - 429 WP_168207526.1 PIN domain-containing protein -
FOE78_RS14475 3241106..3241330 - 225 WP_143986924.1 hypothetical protein -
FOE78_RS14480 3241354..3242340 - 987 WP_210415026.1 prolipoprotein diacylglyceryl transferase -
FOE78_RS14485 3242422..3243153 - 732 WP_143986926.1 cytochrome b/b6 domain-containing protein -
FOE78_RS14490 3243143..3243694 - 552 WP_168207527.1 hypothetical protein -
FOE78_RS14495 3244074..3244358 + 285 WP_210414593.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FOE78_RS14500 3244355..3244627 + 273 WP_143986929.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FOE78_RS14505 3245226..3245963 - 738 WP_168207528.1 thioredoxin domain-containing protein -
FOE78_RS14510 3245938..3246720 - 783 WP_143986931.1 thioredoxin domain-containing protein -
FOE78_RS14515 3246717..3247253 - 537 WP_143986932.1 DoxX family membrane protein -
FOE78_RS14520 3247274..3248206 - 933 WP_143986933.1 tryptophan synthase subunit alpha -
FOE78_RS14525 3248158..3249423 - 1266 WP_143986934.1 tryptophan synthase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10488.17 Da        Isoelectric Point: 10.6005

>T129005 WP_143986929.1 NZ_CP041692:3244355-3244627 [Microlunatus sp. KUDC0627]
VTEPYEVVFTRAARRALERELPEKIAAAAFEFVMGALRENPRRIGKPLREPLAPLYSARRGEYRVIYRILEARLVIEVVS
ISHRRDAHHH

Download         Length: 273 bp

>T129005 NZ_CP041692:3244355-3244627 [Microlunatus sp. KUDC0627]
GTGACCGAACCGTACGAGGTCGTTTTCACCCGCGCTGCCCGTCGAGCCTTGGAGCGCGAACTACCGGAAAAGATCGCCGC
CGCTGCATTCGAGTTCGTCATGGGAGCACTGCGCGAGAATCCGCGCAGAATTGGCAAGCCGCTGCGCGAGCCGTTGGCAC
CGCTCTACTCCGCTCGGCGAGGCGAATACCGGGTCATCTACCGCATACTCGAGGCGCGTCTCGTCATAGAGGTCGTCTCA
ATCTCCCACCGCCGCGACGCCCACCATCACTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10026.11 Da        Isoelectric Point: 4.3586

>AT129005 WP_210414593.1 NZ_CP041692:3244074-3244358 [Microlunatus sp. KUDC0627]
MTTLSVADARANFSKLIESAVTTHERFDVTRNGDRAAVLLSADDYDSLLETVDILSHPDEVAAIRDGLADLAHEDVSSAA
DVRAAMVARGRLTA

Download         Length: 285 bp

>AT129005 NZ_CP041692:3244074-3244358 [Microlunatus sp. KUDC0627]
ATGACTACGCTCTCAGTGGCGGATGCCCGCGCAAACTTCTCCAAACTCATCGAGTCGGCCGTAACCACGCACGAGCGGTT
CGACGTCACCCGAAACGGCGATCGCGCGGCGGTGCTCCTCAGCGCCGACGACTACGACTCGTTGCTGGAGACCGTTGACA
TCCTGAGCCATCCGGACGAAGTCGCAGCCATACGCGACGGCCTCGCCGACCTGGCGCACGAGGACGTGTCTTCTGCTGCT
GACGTGCGGGCCGCCATGGTCGCGCGCGGCAGGCTCACCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References