Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3240675..3241330 Replicon chromosome
Accession NZ_CP041692
Organism Microlunatus sp. KUDC0627

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FOE78_RS14470 Protein ID WP_168207526.1
Coordinates 3240675..3241103 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FOE78_RS14475 Protein ID WP_143986924.1
Coordinates 3241106..3241330 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOE78_RS14465 3235745..3240274 - 4530 WP_143986922.1 glutamate synthase large subunit -
FOE78_RS14470 3240675..3241103 - 429 WP_168207526.1 PIN domain-containing protein Toxin
FOE78_RS14475 3241106..3241330 - 225 WP_143986924.1 hypothetical protein Antitoxin
FOE78_RS14480 3241354..3242340 - 987 WP_210415026.1 prolipoprotein diacylglyceryl transferase -
FOE78_RS14485 3242422..3243153 - 732 WP_143986926.1 cytochrome b/b6 domain-containing protein -
FOE78_RS14490 3243143..3243694 - 552 WP_168207527.1 hypothetical protein -
FOE78_RS14495 3244074..3244358 + 285 WP_210414593.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
FOE78_RS14500 3244355..3244627 + 273 WP_143986929.1 type II toxin-antitoxin system RelE/ParE family toxin -
FOE78_RS14505 3245226..3245963 - 738 WP_168207528.1 thioredoxin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15271.47 Da        Isoelectric Point: 5.4640

>T129004 WP_168207526.1 NZ_CP041692:c3241103-3240675 [Microlunatus sp. KUDC0627]
VTYLLDVNVLIALTHPGHVHHNAAHAWMDTVGAWATTPITESGFVRLLMNPRIAGREVTGAEAIELLRGVRGRDGHSFIG
DESSLADAAIGLDMLVGTKQVTDLHLVNLAKINELVFATFDGRIVQWLSAEERAGVEVIAAV

Download         Length: 429 bp

>T129004 NZ_CP041692:c3241103-3240675 [Microlunatus sp. KUDC0627]
GTGACCTATCTCCTCGATGTGAACGTTCTGATCGCGCTGACCCACCCGGGCCATGTCCATCACAACGCAGCGCACGCATG
GATGGATACGGTAGGCGCTTGGGCCACCACGCCAATCACCGAGAGCGGCTTCGTCCGGTTGCTGATGAACCCTCGGATCG
CCGGCCGTGAAGTCACCGGCGCCGAGGCGATCGAGCTTCTTCGCGGCGTCCGTGGGCGGGACGGTCATTCCTTCATCGGG
GACGAGTCTTCGCTGGCTGATGCCGCGATCGGGCTCGACATGCTGGTGGGCACGAAGCAGGTGACCGATCTGCATCTGGT
CAACCTCGCGAAGATCAACGAACTGGTGTTCGCGACCTTCGACGGGCGAATCGTGCAGTGGCTCAGCGCTGAGGAGCGGG
CTGGGGTCGAGGTCATCGCGGCGGTGTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 7720.76 Da        Isoelectric Point: 4.7185

>AT129004 WP_143986924.1 NZ_CP041692:c3241330-3241106 [Microlunatus sp. KUDC0627]
MRTTLDLDERVLAAARALAAAKNISVGRALSELALRGLAGPASENKTRSGFPVISGVSGHVITDEMVESALEEE

Download         Length: 225 bp

>AT129004 NZ_CP041692:c3241330-3241106 [Microlunatus sp. KUDC0627]
ATGCGGACGACTCTCGATCTGGATGAGCGGGTACTCGCGGCGGCTCGCGCGCTTGCCGCTGCCAAGAACATCTCCGTCGG
CCGCGCATTGTCCGAATTGGCACTGAGGGGGCTGGCCGGACCGGCGAGCGAGAACAAGACGCGGTCTGGATTTCCGGTGA
TCAGCGGTGTAAGCGGCCACGTGATCACTGATGAGATGGTCGAATCCGCGCTCGAAGAGGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References