Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 53923..54572 Replicon chromosome
Accession NZ_CP041692
Organism Microlunatus sp. KUDC0627

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FOE78_RS00250 Protein ID WP_143984544.1
Coordinates 53923..54342 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FOE78_RS00255 Protein ID WP_143988415.1
Coordinates 54339..54572 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOE78_RS00230 49483..50052 + 570 WP_143984541.1 GNAT family N-acetyltransferase -
FOE78_RS00235 50159..52291 - 2133 WP_143984542.1 DEAD/DEAH box helicase -
FOE78_RS00240 52300..53106 - 807 WP_143984543.1 BREX system ATP-binding protein BrxD -
FOE78_RS00245 53069..53752 - 684 WP_210414734.1 NERD domain-containing protein -
FOE78_RS00250 53923..54342 - 420 WP_143984544.1 type II toxin-antitoxin system VapC family toxin Toxin
FOE78_RS00255 54339..54572 - 234 WP_143988415.1 Arc family DNA-binding protein Antitoxin
FOE78_RS00260 54672..56003 - 1332 WP_143984545.1 PLP-dependent aminotransferase family protein -
FOE78_RS00265 56073..56786 + 714 WP_143984546.1 pyridoxamine 5'-phosphate oxidase family protein -
FOE78_RS00270 56875..58911 - 2037 WP_143984547.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-129)

Antitoxin

Arc-like DNA binding domain

(11-43)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15131.20 Da        Isoelectric Point: 4.7278

>T128995 WP_143984544.1 NZ_CP041692:c54342-53923 [Microlunatus sp. KUDC0627]
MIVLDTNVLSEVFRPDPDAQVIDWIETLTGDVAITAITLAELLAGVRRLPAGRRRSKLATQIDSALEPYRETRAILAFDD
RAAESYPNILVARERAGLPIHTADAQIAAICRANSATCATRNTKDFANTGIELVDPWAS

Download         Length: 420 bp

>T128995 NZ_CP041692:c54342-53923 [Microlunatus sp. KUDC0627]
ATGATCGTCCTCGACACGAACGTCCTGTCCGAGGTCTTCCGGCCAGATCCGGATGCGCAGGTCATCGATTGGATCGAGAC
CTTGACTGGCGACGTCGCGATCACGGCGATCACGCTGGCCGAGCTGTTGGCGGGCGTTCGTCGGCTACCTGCCGGTAGGC
GTCGTTCGAAGCTGGCCACGCAGATCGATTCCGCACTGGAGCCATATCGAGAGACCCGCGCGATCCTCGCGTTCGACGAC
CGTGCGGCGGAGTCCTATCCCAACATCCTGGTCGCGCGCGAACGCGCCGGCCTGCCGATCCACACTGCAGATGCTCAGAT
CGCGGCGATCTGTCGAGCAAACTCAGCCACCTGCGCCACCAGGAACACCAAGGACTTCGCCAATACAGGGATCGAACTGG
TCGATCCCTGGGCATCCTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8186.32 Da        Isoelectric Point: 6.4643

>AT128995 WP_143988415.1 NZ_CP041692:c54572-54339 [Microlunatus sp. KUDC0627]
MASVVIRGLDESVKKQLAAQAREHGRSMEAEARDILTKATRQPHIGLALVAAAREVGGVEDLPVPDRTDLARSADLG

Download         Length: 234 bp

>AT128995 NZ_CP041692:c54572-54339 [Microlunatus sp. KUDC0627]
ATGGCATCCGTCGTCATCCGTGGGCTGGACGAGTCCGTCAAGAAGCAGCTCGCAGCACAGGCAAGGGAACATGGCCGGTC
GATGGAGGCGGAGGCTCGCGACATCCTCACCAAGGCCACGCGCCAACCCCACATCGGCCTTGCGCTGGTAGCTGCTGCAC
GGGAGGTCGGTGGCGTCGAGGACTTGCCCGTGCCGGACCGAACTGATCTGGCCCGGTCGGCGGACCTGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References