Detailed information of TA system TA128992

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 2677347..2677870
• Replicon: chromosome
• Accession: NZ_CP041690
• Organism: Youhaiella tibetensis strain fig4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FNA67_RS12910
• Protein ID: WP_147656307.1
• Coordinates: 2677347..2677622 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FNA67_RS12915
• Protein ID: WP_147656308.1
• Coordinates: 2677622..2677870 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FNA67_RS12870	2672466..2672723	+	258	WP_147656301.1	YjhX family toxin	-
FNA67_RS12875	2672773..2672997	-	225	WP_082202452.1	hypothetical protein	-
FNA67_RS12880	2673205..2673972	-	768	WP_147656302.1	pentapeptide repeat-containing protein	-
FNA67_RS12885	2673966..2675450	-	1485	WP_147656303.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	-
FNA67_RS12890	2675447..2675923	-	477	WP_147656304.1	hypothetical protein	-
FNA67_RS12895	2675944..2676426	-	483	WP_147656305.1	GNAT family N-acetyltransferase	-
FNA67_RS12900	2676432..2676719	-	288	WP_049705559.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
FNA67_RS12905	2676811..2677350	-	540	WP_147656306.1	hypothetical protein	-
FNA67_RS12910	2677347..2677622	-	276	WP_147656307.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FNA67_RS12915	2677622..2677870	-	249	WP_147656308.1	ribbon-helix-helix domain-containing protein	Antitoxin
FNA67_RS12920	2677945..2678403	-	459	WP_170267307.1	DUF2442 domain-containing protein	-
FNA67_RS12925	2678773..2679234	+	462	WP_147656310.1	Holliday junction resolvase RuvX	-
FNA67_RS12930	2679316..2680305	+	990	WP_147656311.1	aspartate carbamoyltransferase catalytic subunit	-
FNA67_RS12935	2680302..2681600	+	1299	WP_147656312.1	dihydroorotase	-
FNA67_RS12940	2681597..2682196	+	600	WP_049705564.1	glycerol-3-phosphate 1-O-acyltransferase PlsY	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (6-42)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10644.34 Da
• Isoelectric Point: 10.8246

>T128992 WP_147656307.1 NZ_CP041690:c2677622-2677347 [Youhaiella tibetensis]
MRLRWTSAAQGDLARLHEFLKTDSPGAAARVVQMLVAAPEQLLKAPRLGQRLEEFSPREVRRIIVGRYEMRYEVADQAVF
ILRIWHTREDR

Nucleotide

• Length: 276 bp

>T128992 NZ_CP041690:c2677622-2677347 [Youhaiella tibetensis]
ATGCGTCTGCGGTGGACTTCTGCCGCTCAGGGTGACCTCGCTCGGCTCCACGAGTTTCTTAAGACTGACAGTCCCGGCGC
TGCTGCAAGGGTGGTCCAAATGCTGGTGGCAGCACCCGAGCAGTTGCTCAAGGCACCGCGCCTCGGCCAACGTCTCGAGG
AATTTTCACCCAGGGAGGTTCGCCGCATTATCGTTGGGCGCTATGAAATGCGCTACGAGGTCGCCGATCAAGCGGTCTTT
ATTCTGCGCATCTGGCACACACGGGAAGATCGATGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9230.36 Da
• Isoelectric Point: 4.6742

>AT128992 WP_147656308.1 NZ_CP041690:c2677870-2677622 [Youhaiella tibetensis]
MSTRVLTAHVPEELAERVDQLAARLERSRGWIVKQALTDWVALEDERRHLTLEALADVDEGRLVEHDSMVSWAAGLGEGP
NR

Nucleotide

• Length: 249 bp

>AT128992 NZ_CP041690:c2677870-2677622 [Youhaiella tibetensis]
ATGAGCACTCGTGTCCTTACAGCCCATGTTCCTGAAGAGCTCGCTGAGCGGGTGGACCAACTGGCCGCGCGGCTGGAGCG
GTCGAGGGGCTGGATCGTCAAACAGGCTTTGACCGATTGGGTGGCGCTCGAGGATGAGCGCAGGCACCTCACGCTCGAGG
CGCTCGCCGATGTCGATGAGGGGCGCCTTGTCGAGCATGACAGCATGGTGTCATGGGCGGCGGGGCTCGGCGAGGGCCCC
AATCGCTGA