Detailed information of TA system TA128991

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): BrnTA/BrnT-BrnA
• Location: 989621..990156
• Replicon: chromosome
• Accession: NZ_CP041690
• Organism: Youhaiella tibetensis strain fig4

Toxin (Protein)

• Gene name: brnT
• Uniprot ID: -
• Locus tag: FNA67_RS04800
• Protein ID: WP_147655246.1
• Coordinates: 989908..990156 (-)
• Length: 83 a.a.

Antitoxin (Protein)

• Gene name: brnA
• Uniprot ID: -
• Locus tag: FNA67_RS04795
• Protein ID: WP_147658138.1
• Coordinates: 989621..989899 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FNA67_RS04790	987753..989555	-	1803	WP_147655245.1	DNA mismatch repair endonuclease MutL	-
FNA67_RS04795	989621..989899	-	279	WP_147658138.1	BrnA antitoxin family protein	Antitoxin
FNA67_RS04800	989908..990156	-	249	WP_147655246.1	BrnT family toxin	Toxin
FNA67_RS04805	990264..990713	+	450	WP_147655247.1	nucleoside deaminase	-
FNA67_RS04810	990646..991545	-	900	WP_170267211.1	patatin-like phospholipase family protein	-
FNA67_RS04815	991673..992947	-	1275	WP_147655249.1	phosphoribosylamine--glycine ligase	-
FNA67_RS04820	993086..994525	+	1440	WP_147655250.1	exodeoxyribonuclease VII large subunit	-
FNA67_RS04825	994598..994819	+	222	WP_049704153.1	DUF2093 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-78)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (17-90)

Sequences

Toxin

Protein

• Length: 83 a.a.
• Molecular weight: 8926.27 Da
• Isoelectric Point: 7.0102

>T128991 WP_147655246.1 NZ_CP041690:c990156-989908 [Youhaiella tibetensis]
VRTITWDEPKRLANLAKHGMDFNDLTEDFFLGALVIPARNGRFQAFGSLGDSTISVIFAVLGTEGLSIISMRSASAAERK
LL

Nucleotide

• Length: 249 bp

>T128991 NZ_CP041690:c990156-989908 [Youhaiella tibetensis]
GTGCGAACCATCACCTGGGATGAACCGAAGCGCCTCGCCAACCTTGCCAAACACGGCATGGACTTCAACGATTTGACGGA
AGACTTCTTCCTCGGCGCTCTCGTCATCCCCGCCCGGAACGGCCGTTTCCAGGCCTTCGGCTCTCTCGGGGACAGCACGA
TCTCGGTGATTTTCGCTGTGCTCGGCACGGAAGGGCTGTCGATCATTTCGATGCGCTCCGCCAGTGCGGCAGAAAGGAAG
CTATTGTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10085.41 Da
• Isoelectric Point: 9.7653

>AT128991 WP_147658138.1 NZ_CP041690:c989899-989621 [Youhaiella tibetensis]
MKPGQGYAQEDWDAVSDNPEISKSQLSKARPFAEALPELAEKMRNAGGRPRSDNPKQLVSIRLDADVLDRLKSEGPGWQT
RANAILKKAVGL

Nucleotide

• Length: 279 bp

>AT128991 NZ_CP041690:c989899-989621 [Youhaiella tibetensis]
ATGAAGCCCGGCCAGGGCTATGCGCAGGAAGATTGGGATGCCGTCTCGGACAATCCCGAGATTTCCAAAAGCCAGCTTTC
CAAGGCGCGCCCCTTCGCCGAGGCCCTCCCGGAACTCGCCGAAAAGATGCGGAATGCCGGCGGGCGCCCGCGCAGCGACA
ACCCCAAGCAGCTTGTGTCCATCCGCCTCGACGCCGACGTTCTCGATCGCCTCAAGTCAGAAGGACCCGGCTGGCAGACG
CGCGCCAATGCCATCCTCAAGAAGGCTGTCGGCCTCTAG