Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 1507998..1509625 Replicon chromosome
Accession NZ_CP041660
Organism Catenovulum sediminis strain WS1-A

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag FNT16_RS06075 Protein ID WP_185976705.1
Coordinates 1507998..1509362 (-) Length 455 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag FNT16_RS06080 Protein ID WP_185976706.1
Coordinates 1509356..1509625 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNT16_RS06055 1504258..1504548 + 291 WP_143870688.1 helix-turn-helix domain-containing protein -
FNT16_RS06060 1504538..1505887 + 1350 WP_143870689.1 type II toxin-antitoxin system HipA family toxin -
FNT16_RS06065 1505906..1506910 + 1005 WP_143870690.1 SEC-C domain-containing protein -
FNT16_RS06070 1506921..1507884 + 964 Protein_1168 hypothetical protein -
FNT16_RS06075 1507998..1509362 - 1365 WP_185976705.1 type II toxin-antitoxin system HipA family toxin Toxin
FNT16_RS06080 1509356..1509625 - 270 WP_185976706.1 helix-turn-helix transcriptional regulator Antitoxin
FNT16_RS06085 1510059..1510370 - 312 WP_143870692.1 type II toxin-antitoxin system RelE/ParE family toxin -
FNT16_RS06090 1510370..1510609 - 240 WP_143870693.1 hypothetical protein -
FNT16_RS06095 1510683..1510991 - 309 WP_143870694.1 AlpA family phage regulatory protein -
FNT16_RS06100 1511009..1512168 + 1160 WP_143870695.1 IS3 family transposase -
FNT16_RS06105 1512118..1512348 - 231 WP_143870696.1 hypothetical protein -
FNT16_RS06110 1512502..1514073 - 1572 WP_143869684.1 IS66 family transposase -
FNT16_RS06115 1514109..1514474 - 366 WP_143869685.1 IS66 family insertion sequence element accessory protein TnpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(11-111)

Antitoxin

Cro/C1-type helix-turn-helix domain

(19-68)


Sequences

Toxin        


Download         Length: 455 a.a.        Molecular weight: 50888.52 Da        Isoelectric Point: 7.6545

>T128949 WP_185976705.1 NZ_CP041660:c1509362-1507998 [Catenovulum sediminis]
MVIAKRKVSALAIWMNAEFVGTWRIKSGVDELQYADEWLASARGRPLSLSLPFTPGNQPIKGDVVSFYFDNLLPDSRDIR
ERLARRFITASTKVFDLLVELGRDCVGAIQLLPEGDKPQNIKQIQYKPLNEQQVAGILNKAVDTYPLGRLDDDDSLRISL
AGAQEKTAHLWYNNQWCEPLGETPTTHIFKLPMGLVGNMKVDMEASVENEWLCSKIIAEFDIPIAHCDMGSFAGKKALIV
ERFDRKLSSDGSWIIRLPQEDFCQATGLSSLLKYQSDGGLSVEDCMKLLSSSENAAVDKQNFFKAQIAFYLLAATDGHAK
NFSITHLPDNKYKLTPLYDVLSIHPLIGNKANQIAKQKVKMAMALRCTKKTGSKNYYQLQKIQYRHFIQQGKEVGFTEAE
VSELINSVVNVVDTVIENVSTILPKDFPADISDKIFAGMKAQANKLSVHTYTKW

Download         Length: 1365 bp

>T128949 NZ_CP041660:c1509362-1507998 [Catenovulum sediminis]
ATGGTAATAGCAAAACGTAAAGTAAGCGCATTAGCTATTTGGATGAACGCAGAGTTTGTTGGTACTTGGCGAATAAAATC
AGGTGTTGATGAATTGCAATACGCGGATGAATGGCTAGCAAGCGCACGAGGTCGCCCTTTATCTTTATCACTACCATTTA
CTCCAGGAAACCAACCAATTAAAGGCGATGTGGTTTCATTTTACTTTGATAATTTACTGCCTGATAGTAGAGATATACGT
GAACGATTAGCAAGGCGGTTTATTACGGCAAGCACCAAGGTATTTGATTTACTCGTTGAGCTAGGTCGTGATTGTGTGGG
GGCAATTCAATTGCTACCAGAAGGCGATAAGCCGCAGAATATTAAACAAATTCAGTATAAACCGCTAAATGAACAGCAAG
TTGCGGGAATACTAAATAAAGCTGTTGATACCTATCCACTAGGTCGTTTAGACGACGATGATTCCTTAAGAATTTCACTT
GCTGGTGCTCAAGAAAAGACTGCGCATCTGTGGTACAATAACCAATGGTGTGAACCTTTAGGGGAAACGCCAACTACACA
CATATTTAAGCTGCCAATGGGGTTAGTTGGCAATATGAAAGTAGACATGGAAGCCTCTGTTGAAAATGAATGGTTATGCT
CGAAGATAATCGCCGAATTTGATATTCCGATTGCGCATTGTGACATGGGATCTTTTGCGGGTAAAAAAGCACTTATTGTT
GAGCGCTTTGATCGTAAATTATCAAGTGATGGCTCATGGATTATTCGATTGCCTCAAGAAGATTTTTGTCAAGCAACTGG
TTTGTCATCATTACTCAAATATCAAAGCGATGGCGGTTTGAGCGTCGAAGATTGTATGAAGCTACTTTCCAGTAGTGAAA
ATGCAGCTGTTGATAAACAAAACTTTTTTAAAGCGCAAATAGCTTTCTATTTACTTGCAGCAACCGATGGCCATGCAAAA
AACTTTAGCATTACTCATTTGCCAGACAATAAATACAAACTCACACCGCTATATGATGTACTTTCTATTCACCCGCTTAT
TGGTAATAAGGCGAATCAAATTGCTAAACAGAAAGTAAAAATGGCAATGGCTCTGCGTTGTACAAAAAAGACTGGTAGCA
AAAATTACTATCAATTACAGAAAATACAATATCGTCATTTCATTCAACAAGGCAAAGAAGTGGGGTTTACCGAGGCAGAA
GTATCTGAGCTTATTAACTCAGTGGTTAACGTTGTTGATACTGTTATCGAAAATGTCAGTACAATCCTCCCTAAAGACTT
TCCAGCAGATATATCGGATAAGATCTTTGCAGGAATGAAAGCGCAAGCAAACAAGCTAAGCGTGCATACTTACACCAAGT
GGTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10038.57 Da        Isoelectric Point: 8.4930

>AT128949 WP_185976706.1 NZ_CP041660:c1509625-1509356 [Catenovulum sediminis]
VNYTINTLDQIKPILVGFRKTNGLSQKALAEKLGISQQSYQALESAPQKVTIERMFKVLSILDIKLQFVEKNKPLESSLS
SSELAQDEW

Download         Length: 270 bp

>AT128949 NZ_CP041660:c1509625-1509356 [Catenovulum sediminis]
GTGAATTACACAATTAATACTCTTGATCAAATTAAACCGATTCTTGTTGGGTTTAGAAAAACTAATGGGCTTTCGCAAAA
AGCGTTAGCCGAAAAACTGGGTATTAGCCAACAAAGTTATCAAGCACTTGAAAGCGCACCACAAAAGGTAACGATAGAAC
GCATGTTTAAGGTGCTTTCTATTTTGGATATAAAGCTACAATTTGTAGAAAAAAATAAACCGCTAGAGAGTAGCCTATCC
AGTAGCGAACTCGCGCAGGATGAATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References