Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 6036109..6036776 Replicon chromosome
Accession NZ_CP041656
Organism Bradyrhizobium cosmicum strain 58S1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FNV92_RS28635 Protein ID WP_143844883.1
Coordinates 6036109..6036519 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FNV92_RS28640 Protein ID WP_143844884.1
Coordinates 6036519..6036776 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNV92_RS28610 6031551..6032237 - 687 WP_015686485.1 DJ-1/PfpI family protein -
FNV92_RS28615 6032329..6033270 + 942 WP_015686484.1 GlxA family transcriptional regulator -
FNV92_RS28620 6033308..6034138 - 831 WP_143844880.1 helix-turn-helix transcriptional regulator -
FNV92_RS28625 6034276..6034971 + 696 WP_143844881.1 class I SAM-dependent methyltransferase -
FNV92_RS28630 6035069..6036067 - 999 WP_143844882.1 Na+-dependent transporter -
FNV92_RS28635 6036109..6036519 - 411 WP_143844883.1 type II toxin-antitoxin system VapC family toxin Toxin
FNV92_RS28640 6036519..6036776 - 258 WP_143844884.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FNV92_RS28645 6036884..6037831 - 948 WP_143844885.1 alpha/beta hydrolase -
FNV92_RS28650 6038038..6039069 + 1032 WP_143844886.1 DUF2155 domain-containing protein -
FNV92_RS28655 6039107..6039787 - 681 WP_143844887.1 leucyl/phenylalanyl-tRNA--protein transferase -
FNV92_RS28660 6039852..6040955 - 1104 WP_143844888.1 response regulator -
FNV92_RS28665 6040952..6041392 - 441 WP_143844889.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-56)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15012.26 Da        Isoelectric Point: 8.7358

>T128943 WP_143844883.1 NZ_CP041656:c6036519-6036109 [Bradyrhizobium cosmicum]
MFLLDTVTLSELRRTRRNPSVVAWMERQRTADLFLSVVSIGEIERGIARQRAADPSFADALAGWLDRLLALYGTQILPFD
LQTARRWGTLSAALGNESADLMIAATALEHGLTVVTRNVSDFKPAGVRIVNPFEGK

Download         Length: 411 bp

>T128943 NZ_CP041656:c6036519-6036109 [Bradyrhizobium cosmicum]
ATGTTTCTGCTCGACACCGTCACGCTGTCCGAACTGCGTCGGACCAGACGCAACCCGTCCGTGGTCGCCTGGATGGAGCG
GCAGCGAACGGCCGATCTTTTCCTCAGCGTCGTCAGCATCGGCGAAATCGAACGCGGAATCGCGCGTCAACGCGCTGCAG
ATCCGAGCTTTGCAGATGCGCTCGCCGGCTGGCTGGATCGCCTTCTCGCTCTCTACGGCACACAAATCCTGCCGTTTGAT
CTGCAGACCGCACGTCGCTGGGGGACTCTCAGTGCCGCGCTCGGCAATGAAAGCGCCGACCTCATGATCGCCGCCACGGC
GCTCGAGCACGGGCTGACCGTCGTGACGCGCAATGTGTCGGATTTCAAGCCGGCGGGAGTCCGCATCGTCAATCCATTTG
AAGGCAAGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9638.05 Da        Isoelectric Point: 8.9140

>AT128943 WP_143844884.1 NZ_CP041656:c6036776-6036519 [Bradyrhizobium cosmicum]
MSKRVWSVQDAKNRFSEVVIAAQRAPQTVTRHGKPAVVILNAAEFERLQELQRARAPSLSDLLLEMPQDDEEFPRARIAI
RDVGL

Download         Length: 258 bp

>AT128943 NZ_CP041656:c6036776-6036519 [Bradyrhizobium cosmicum]
ATGTCCAAGCGAGTCTGGTCGGTGCAGGACGCAAAGAACCGCTTCAGCGAGGTGGTCATTGCGGCGCAACGCGCGCCACA
GACCGTGACGCGGCATGGCAAACCCGCTGTGGTGATCCTGAATGCCGCGGAGTTTGAACGCCTGCAGGAGCTGCAACGCG
CGCGGGCACCCTCTCTTTCCGATCTGCTTCTTGAAATGCCGCAAGACGACGAGGAATTTCCGCGCGCGCGCATCGCAATT
CGTGACGTCGGCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References