Detailed information of TA system TA128941

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): CapRel-ATcapRel/-
• Location: 5118481..5119478
• Replicon: chromosome
• Accession: NZ_CP041647
• Organism: Rhodococcus hoagii strain WY

Toxin (Protein)

• Gene name: capRel
• Uniprot ID: -
• Locus tag: FNU77_RS24230
• Protein ID: WP_175280154.1
• Coordinates: 5118732..5119478 (-)
• Length: 249 a.a.

Antitoxin (Protein)

• Gene name: ATcapRel
• Uniprot ID: -
• Locus tag: FNU77_RS24225
• Protein ID: WP_143524956.1
• Coordinates: 5118481..5118723 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FNU77_RS24200	5114043..5114516	+	474	Protein_4708	holin	-
FNU77_RS24205	5114652..5115131	+	480	WP_143524947.1	hypothetical protein	-
FNU77_RS24210	5115118..5115849	+	732	WP_143524948.1	hypothetical protein	-
FNU77_RS24215	5115842..5117524	+	1683	WP_143524949.1	hypothetical protein	-
FNU77_RS24220	5117524..5118408	+	885	WP_143524950.1	hypothetical protein	-
FNU77_RS24225	5118481..5118723	-	243	WP_143524956.1	hypothetical protein	Antitoxin
FNU77_RS24230	5118732..5119478	-	747	WP_175280154.1	RelA/SpoT domain-containing protein	Toxin
FNU77_RS24235	5119757..5120035	-	279	WP_143524817.1	hypothetical protein	-
FNU77_RS24240	5120032..5120238	-	207	WP_143524818.1	transcriptional regulator	-
FNU77_RS24245	5120235..5120417	-	183	WP_084956584.1	hypothetical protein	-
FNU77_RS24250	5121328..5121816	+	489	WP_143524819.1	hypothetical protein	-
FNU77_RS24255	5122674..5123588	+	915	WP_175280140.1	Lsr2 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RelA/SpoT (83-181)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 249 a.a.
• Molecular weight: 27998.09 Da
• Isoelectric Point: 10.2843

>T128941 WP_175280154.1 NZ_CP041647:c5119478-5118732 [Rhodococcus hoagii]
VPQSRQVPTPSKNQVNKAGDALRSFFDYVRTRPDPIADYPTERLAAASAALDVLFAWRSAHARPLQVASMGLRSRVQTEG
CRVEVSQRLKRVPTIIDKLHRQPKMALARMADIGGCRAVLDSIDEVRRVEKRLCKGRPPKTYHDYIAEPKESGYRGVHVI
SEYRGRLIEVQLRTRTMHEWAYMVEKVTTQIGHDVKSGRGPAKVHDWFQAVSEAMALEEQGLTVDGTLAKRIVELRSEAE
PYLRGGRS

Nucleotide

• Length: 747 bp

>T128941 NZ_CP041647:c5119478-5118732 [Rhodococcus hoagii]
GTGCCTCAATCCCGTCAGGTGCCCACGCCCAGCAAGAACCAAGTGAATAAGGCAGGCGACGCGCTTCGCTCCTTCTTCGA
CTACGTGCGGACCCGCCCCGATCCCATCGCGGACTATCCAACAGAGCGACTAGCCGCAGCCAGTGCGGCGCTCGACGTCC
TCTTCGCCTGGCGTTCGGCCCATGCCAGACCGCTTCAGGTTGCGAGCATGGGCTTGCGTTCTCGGGTCCAAACGGAAGGC
TGCCGGGTCGAGGTGTCCCAACGCCTCAAGCGCGTGCCGACCATCATCGACAAGCTGCACCGGCAGCCCAAGATGGCACT
CGCGCGCATGGCTGACATCGGCGGTTGCCGGGCCGTCCTCGACTCCATCGATGAGGTGCGACGGGTTGAGAAGCGCCTGT
GTAAAGGGCGGCCACCGAAGACCTACCACGACTACATCGCTGAGCCGAAGGAATCGGGATACCGTGGAGTGCACGTGATT
AGCGAGTACCGCGGACGGCTGATCGAGGTTCAGCTGCGTACCCGAACCATGCACGAGTGGGCCTACATGGTCGAGAAGGT
GACCACTCAAATCGGTCACGACGTAAAGTCCGGCAGAGGGCCAGCGAAGGTTCACGACTGGTTCCAGGCTGTGTCCGAAG
CGATGGCCCTTGAGGAGCAGGGCTTGACAGTGGATGGCACACTAGCAAAGAGAATCGTTGAGCTTCGGTCAGAAGCAGAG
CCATATTTGAGGGGAGGCCGCTCTTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9029.06 Da
• Isoelectric Point: 4.4763

>AT128941 WP_143524956.1 NZ_CP041647:c5118723-5118481 [Rhodococcus hoagii]
IKHFLLVFDHSRAELVDLQEFEEDTRAAMAAYAEKEREHLNNGDSIEIVLIGSDSLETIKLTHANYFDGTVAVSRYFAGV

Nucleotide

• Length: 243 bp

>AT128941 NZ_CP041647:c5118723-5118481 [Rhodococcus hoagii]
ATCAAGCACTTCCTCCTGGTGTTCGACCACTCCCGCGCGGAGTTGGTTGACCTGCAGGAATTCGAGGAAGACACGCGGGC
AGCGATGGCCGCTTACGCCGAGAAGGAGCGGGAGCACCTCAACAATGGCGACTCGATCGAGATCGTGCTGATCGGCTCCG
ACTCTCTGGAAACGATCAAGCTCACCCACGCGAACTACTTCGATGGCACCGTAGCCGTATCGCGGTACTTCGCCGGCGTC
TAG