Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3497215..3497360 Replicon chromosome
Accession NZ_CP041644
Organism Klebsiella pneumoniae strain NKU_Kleb8A7

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3497251..3497353 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3497215..3497360 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOA47_RS16880 3492345..3494405 + 2061 WP_004151449.1 oligopeptidase B -
FOA47_RS16885 3494409..3495068 - 660 WP_002911407.1 exodeoxyribonuclease X -
FOA47_RS16890 3495147..3495377 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FOA47_RS16895 3495490..3495864 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FOA47_RS16900 3495868..3496737 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
FOA47_RS16905 3496754..3497092 + 339 WP_004189269.1 YebY family protein -
- 3497215..3497360 - 146 - - Antitoxin
- 3497251..3497353 + 103 - - Toxin
FOA47_RS16915 3497727..3497870 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FOA47_RS16920 3497975..3498943 - 969 WP_004151446.1 VirK/YbjX family protein -
FOA47_RS16925 3499100..3499753 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
FOA47_RS16930 3499750..3499941 - 192 WP_002911395.1 YebW family protein -
FOA47_RS16935 3500039..3500278 - 240 WP_002911393.1 YebV family protein -
FOA47_RS16940 3500394..3501827 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T128929 NZ_CP041644:3497251-3497353 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT128929 NZ_CP041644:c3497360-3497215 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References