Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1877493..1877638 Replicon chromosome
Accession NZ_CP041639
Organism Klebsiella pneumoniae strain PIMB15ND2KP27

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1877529..1877631 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1877493..1877638 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DIJ67_RS09390 1872623..1874683 + 2061 WP_004151449.1 oligopeptidase B -
DIJ67_RS09395 1874687..1875346 - 660 WP_002911407.1 exodeoxyribonuclease X -
DIJ67_RS09400 1875425..1875655 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DIJ67_RS09405 1875768..1876142 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DIJ67_RS09410 1876146..1877015 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
DIJ67_RS09415 1877032..1877370 + 339 WP_009307539.1 YebY family protein -
- 1877493..1877638 - 146 - - Antitoxin
- 1877529..1877631 + 103 - - Toxin
DIJ67_RS09425 1878007..1878150 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DIJ67_RS09430 1878255..1879223 - 969 WP_004151446.1 VirK/YbjX family protein -
DIJ67_RS09435 1879380..1880033 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
DIJ67_RS09440 1880030..1880221 - 192 WP_002911395.1 YebW family protein -
DIJ67_RS09445 1880319..1880558 - 240 WP_002911393.1 YebV family protein -
DIJ67_RS09450 1880674..1882107 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T128901 NZ_CP041639:1877529-1877631 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT128901 NZ_CP041639:c1877638-1877493 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References