Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2785436..2786024 Replicon chromosome
Accession NZ_CP041637
Organism Formosa sediminum strain PS13

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FNB79_RS12160 Protein ID WP_143381558.1
Coordinates 2785722..2786024 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FNB79_RS12155 Protein ID WP_143381557.1
Coordinates 2785436..2785720 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNB79_RS12125 2780549..2781415 - 867 WP_143381553.1 hypothetical protein -
FNB79_RS12130 2781634..2782521 - 888 WP_143381554.1 DUF3592 domain-containing protein -
FNB79_RS12135 2782684..2783493 - 810 WP_143381117.1 SDR family oxidoreductase -
FNB79_RS12140 2783576..2784133 - 558 WP_143381118.1 Crp/Fnr family transcriptional regulator -
FNB79_RS12145 2784397..2785257 - 861 WP_185967770.1 alpha/beta fold hydrolase -
FNB79_RS12155 2785436..2785720 - 285 WP_143381557.1 putative addiction module antidote protein Antitoxin
FNB79_RS12160 2785722..2786024 - 303 WP_143381558.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNB79_RS12165 2786255..2786776 - 522 WP_143381523.1 hypothetical protein -
FNB79_RS12170 2786962..2787363 - 402 WP_143381559.1 hypothetical protein -
FNB79_RS12175 2787528..2787989 - 462 WP_143381560.1 RDD family protein -
FNB79_RS12180 2787990..2788283 - 294 WP_143381561.1 barstar family protein -
FNB79_RS12185 2788997..2789788 - 792 WP_143381562.1 hypothetical protein -
FNB79_RS12190 2789913..2790386 - 474 WP_143381563.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2725353..2794794 69441


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(2-91)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11856.95 Da        Isoelectric Point: 10.3575

>T128897 WP_143381558.1 NZ_CP041637:c2786024-2785722 [Formosa sediminum]
MIITEKTPEFDKWIRKLKDIRAKAKVLFRIQKLETDEHFGDCKPVGDGISEMRINYAKGYRVYFKEKENKIVILLIGGDK
STQQKDIEKAKKIWNRIKDK

Download         Length: 303 bp

>T128897 NZ_CP041637:c2786024-2785722 [Formosa sediminum]
ATGATAATAACCGAAAAGACACCTGAATTTGATAAGTGGATTAGAAAGCTAAAAGACATCAGAGCTAAAGCAAAAGTTCT
CTTTAGAATTCAGAAACTCGAAACCGATGAACATTTTGGTGATTGTAAACCTGTTGGTGACGGAATTAGTGAAATGCGAA
TCAATTATGCTAAAGGCTATCGAGTATATTTTAAAGAAAAAGAAAATAAAATTGTTATTCTTTTAATTGGCGGAGACAAA
TCGACCCAACAAAAAGATATAGAAAAAGCAAAAAAAATCTGGAACAGAATAAAAGACAAATAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10030.63 Da        Isoelectric Point: 4.7085

>AT128897 WP_143381557.1 NZ_CP041637:c2785720-2785436 [Formosa sediminum]
MATTKFDIADYLDSEEMIAEYLNTVLEDGDSSDLIVAIGNIAKSIGMTKIAEKTGMSRPSLYKALSDGAKPQFGTIMKVL
KAIGGQINVKPMSA

Download         Length: 285 bp

>AT128897 NZ_CP041637:c2785720-2785436 [Formosa sediminum]
ATGGCAACTACAAAATTTGACATAGCGGACTATTTAGACAGCGAAGAAATGATTGCTGAATATCTGAATACTGTTCTCGA
AGATGGAGACAGTTCTGATTTAATTGTGGCAATTGGGAACATTGCCAAGTCAATCGGAATGACCAAAATTGCGGAAAAAA
CAGGAATGAGCAGACCAAGTTTGTACAAAGCTTTATCCGACGGAGCAAAACCTCAATTTGGAACAATAATGAAAGTTTTG
AAAGCGATTGGCGGGCAAATTAATGTCAAACCAATGTCTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References