Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 162534..162802 Replicon chromosome
Accession NZ_CP041620
Organism Shigella flexneri strain C32

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 162662..162764 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 162534..162802 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNL95_RS01545 159087..159749 - 663 WP_000944258.1 exodeoxyribonuclease X -
FNL95_RS01550 159773..160429 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
FNL95_RS01555 160531..160761 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FNL95_RS01560 160900..161274 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FNL95_RS01565 161278..162150 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
FNL95_RS01570 162163..162504 + 342 WP_000984819.1 YebY family protein -
- 162534..162802 - 269 - - Antitoxin
- 162662..162764 + 103 - - Toxin
FNL95_RS01575 162899..163555 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
FNL95_RS01580 163556..163747 - 192 WP_024186842.1 YebW family protein -
FNL95_RS01585 163852..164088 - 237 WP_001295499.1 DUF1480 family protein -
FNL95_RS01590 164207..165646 - 1440 WP_024186841.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T128771 NZ_CP041620:162662-162764 [Shigella flexneri]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT128771 NZ_CP041620:c162802-162534 [Shigella flexneri]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References