Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 641421..642081 Replicon chromosome
Accession NZ_CP041616
Organism Ornithinimicrobium sp. H23M54

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FNH13_RS02880 Protein ID WP_143782065.1
Coordinates 641641..642081 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FNH13_RS02875 Protein ID WP_143782064.1
Coordinates 641421..641648 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNH13_RS02855 637698..637922 - 225 WP_143782061.1 hypothetical protein -
FNH13_RS02860 637919..639100 - 1182 WP_143782062.1 glycosyltransferase -
FNH13_RS02865 639100..640932 - 1833 WP_143782063.1 phosphoenolpyruvate carboxykinase (GTP) -
FNH13_RS02875 641421..641648 + 228 WP_143782064.1 hypothetical protein Antitoxin
FNH13_RS02880 641641..642081 + 441 WP_143782065.1 hypothetical protein Toxin
FNH13_RS02885 642447..642728 - 282 WP_143782066.1 hypothetical protein -
FNH13_RS02890 642821..643372 + 552 WP_143782067.1 hypothetical protein -
FNH13_RS18930 643420..643584 + 165 WP_165699991.1 PH domain-containing protein -
FNH13_RS02895 643573..644427 - 855 WP_143782068.1 TIGR03620 family F420-dependent LLM class oxidoreductase -
FNH13_RS02900 644453..646663 - 2211 WP_143782069.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(8-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 16138.71 Da        Isoelectric Point: 9.2302

>T128762 WP_143782065.1 NZ_CP041616:641641-642081 [Ornithinimicrobium sp. H23M54]
MTERRVTLFDVNALVALALTTHQHHHAAHRFLRALAGRWATTPLTESGLFRLLLNPLVTGSQRSAPEVMAILQGMRADPR
WTFLEDSTALAEPMVDITVLMGHRQVTDLHLVNVAARHDGVLATFDAAIPSWLAPKDRPRTVVIPA

Download         Length: 441 bp

>T128762 NZ_CP041616:641641-642081 [Ornithinimicrobium sp. H23M54]
ATGACTGAACGGCGGGTCACTCTCTTCGACGTCAACGCCCTCGTTGCCTTAGCTCTGACCACCCATCAGCACCATCATGC
CGCGCATCGATTTCTCAGGGCACTTGCGGGTCGATGGGCGACCACGCCACTCACCGAGTCCGGCCTTTTCCGGCTGCTGC
TCAACCCGCTGGTCACCGGTTCCCAGCGGTCGGCGCCCGAGGTGATGGCCATCCTCCAGGGCATGCGTGCAGATCCGAGA
TGGACCTTCCTGGAGGACTCGACGGCCCTGGCGGAACCGATGGTTGACATCACGGTCCTCATGGGACACCGGCAGGTCAC
TGATCTGCACCTGGTCAATGTGGCAGCACGACACGACGGCGTGCTTGCCACCTTCGATGCCGCCATCCCGTCGTGGCTCG
CCCCGAAGGATCGCCCCCGCACTGTCGTGATCCCAGCCTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8194.34 Da        Isoelectric Point: 4.4702

>AT128762 WP_143782064.1 NZ_CP041616:641421-641648 [Ornithinimicrobium sp. H23M54]
MRTTLEIDDQIMAAARSLARSRGISLGAAVSELARRGLMRSVTTQVDMHYSPFPVMAGDESVLVTDELIADLRDD

Download         Length: 228 bp

>AT128762 NZ_CP041616:641421-641648 [Ornithinimicrobium sp. H23M54]
ATGCGGACAACCTTGGAGATCGACGACCAGATCATGGCCGCGGCGCGTTCCCTGGCGCGCAGTCGCGGGATCTCACTGGG
CGCAGCGGTCTCCGAGCTCGCCCGTCGAGGCCTGATGCGGTCGGTCACGACTCAGGTCGACATGCACTACAGTCCCTTCC
CTGTCATGGCCGGTGACGAGTCGGTCCTGGTCACAGATGAGCTCATCGCGGACCTGCGCGATGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References