Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018762..2019033 Replicon chromosome
Accession NZ_CP041452
Organism Escherichia coli strain YPE3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018892..2018995 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018762..2019033 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNP78_RS10485 2015317..2015979 - 663 WP_000944258.1 exodeoxyribonuclease X -
FNP78_RS10490 2016003..2016659 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FNP78_RS10495 2016761..2016991 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FNP78_RS10500 2017130..2017504 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FNP78_RS10505 2017508..2018380 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
FNP78_RS10510 2018393..2018734 + 342 WP_000976472.1 YebY family protein -
- 2018762..2019033 - 272 - - Antitoxin
- 2018892..2018995 + 104 - - Toxin
FNP78_RS10515 2019130..2019786 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
FNP78_RS10520 2019787..2019978 - 192 WP_001338167.1 YebW family protein -
FNP78_RS10525 2020083..2020319 - 237 WP_001338166.1 DUF1480 family protein -
FNP78_RS10530 2020437..2021876 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T128674 NZ_CP041452:2018892-2018995 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT128674 NZ_CP041452:c2019033-2018762 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References