Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2021508..2021779 Replicon chromosome
Accession NZ_CP041437
Organism Escherichia coli strain STEC005

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2021638..2021741 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2021508..2021779 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNE80_RS09580 2018063..2018725 - 663 WP_000944256.1 exodeoxyribonuclease X -
FNE80_RS09585 2018749..2019405 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FNE80_RS09590 2019507..2019737 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FNE80_RS09595 2019876..2020250 + 375 WP_000204699.1 CopC domain-containing protein YobA -
FNE80_RS09600 2020254..2021126 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
FNE80_RS09605 2021139..2021480 + 342 WP_000976492.1 YebY family protein -
- 2021508..2021779 - 272 - - Antitoxin
- 2021638..2021741 + 104 - - Toxin
FNE80_RS09610 2021876..2022532 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
FNE80_RS09615 2022533..2022724 - 192 WP_001296140.1 YebW family protein -
FNE80_RS09620 2022829..2023065 - 237 WP_001295499.1 DUF1480 family protein -
FNE80_RS09625 2023183..2024622 - 1440 WP_001512833.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T128591 NZ_CP041437:2021638-2021741 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT128591 NZ_CP041437:c2021779-2021508 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGTAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References