Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2085682..2085953 Replicon chromosome
Accession NZ_CP041435
Organism Escherichia coli strain STEC309

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2085812..2085915 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2085682..2085953 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNE81_RS10055 2082237..2082899 - 663 WP_000944256.1 exodeoxyribonuclease X -
FNE81_RS10060 2082923..2083579 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
FNE81_RS10065 2083681..2083911 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FNE81_RS10070 2084050..2084424 + 375 WP_000204699.1 CopC domain-containing protein YobA -
FNE81_RS10075 2084428..2085300 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
FNE81_RS10080 2085313..2085654 + 342 WP_000976472.1 YebY family protein -
- 2085682..2085953 - 272 - - Antitoxin
- 2085812..2085915 + 104 - - Toxin
FNE81_RS10085 2086050..2086706 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FNE81_RS10090 2086707..2086898 - 192 WP_001296140.1 YebW family protein -
FNE81_RS10095 2087003..2087239 - 237 WP_001295499.1 DUF1480 family protein -
FNE81_RS10100 2087357..2088796 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2015820..2101792 85972


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T128563 NZ_CP041435:2085812-2085915 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT128563 NZ_CP041435:c2085953-2085682 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References