Detailed information of TA system TA128269

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 3482391..3483043
• Replicon: chromosome
• Accession: NZ_CP041387
• Organism: Rhodopseudomonas palustris strain GJ-22

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: FLL57_RS15900
• Protein ID: WP_142883384.1
• Coordinates: 3482639..3483043 (+)
• Length: 135 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: Q6N2A9
• Locus tag: FLL57_RS15895
• Protein ID: WP_011159676.1
• Coordinates: 3482391..3482642 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FLL57_RS15885	3477755..3478138	-	384	WP_013504000.1	phasin	-
FLL57_RS15890	3478477..3482064	+	3588	WP_142883383.1	PAS domain-containing protein	-
FLL57_RS15895	3482391..3482642	+	252	WP_011159676.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
FLL57_RS15900	3482639..3483043	+	405	WP_142883384.1	type II toxin-antitoxin system VapC family toxin	Toxin
FLL57_RS15905	3483127..3483837	+	711	WP_013504003.1	Crp/Fnr family transcriptional regulator	-
FLL57_RS15910	3483810..3484034	-	225	WP_142883385.1	DUF1858 domain-containing protein	-
FLL57_RS15915	3484270..3485382	+	1113	WP_142883386.1	nitrite reductase, copper-containing	-
FLL57_RS15920	3485523..3486404	+	882	WP_142883387.1	SUMF1/EgtB/PvdO family nonheme iron enzyme	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-126)

Antitoxin

• Antitoxin VapB-like (1-82)

Sequences

Toxin

Protein

• Length: 135 a.a.
• Molecular weight: 14407.56 Da
• Isoelectric Point: 5.1454

>T128269 WP_142883384.1 NZ_CP041387:3482639-3483043 [Rhodopseudomonas palustris]
VIVIDTSAIIAIFREEQEAAQFARLIASDDQPVLSSGNLLEIAIVLRGLKDVQPAKAERWLDDFIAAAGIRIEPVTTEQT
GYARSAHLRFGKGTGHKAALNYGDCFAYALAKALNAPLLCKGNDFPLTDIPLVA

Nucleotide

• Length: 405 bp

>T128269 NZ_CP041387:3482639-3483043 [Rhodopseudomonas palustris]
GTGATCGTCATCGACACGTCGGCGATCATTGCGATCTTTCGCGAGGAGCAGGAGGCAGCCCAGTTCGCGCGGCTGATCGC
CTCCGACGATCAACCGGTCCTATCCTCAGGCAATTTGCTGGAGATTGCGATCGTTCTCCGTGGACTAAAGGACGTTCAGC
CGGCCAAAGCCGAACGATGGCTTGATGACTTTATCGCGGCGGCCGGCATCCGGATCGAGCCCGTGACCACCGAGCAGACC
GGATACGCGCGTTCGGCGCATTTGCGGTTCGGGAAAGGGACCGGCCACAAAGCAGCTCTCAACTACGGAGATTGCTTCGC
CTACGCGCTGGCCAAAGCTCTGAATGCCCCCTTGCTGTGCAAGGGCAACGACTTTCCGCTGACCGATATTCCGCTTGTCG
CGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9293.42 Da
• Isoelectric Point: 6.7249

>AT128269 WP_011159676.1 NZ_CP041387:3482391-3482642 [Rhodopseudomonas palustris]
MHLNIKNDEAHQLATELARMTGESLTAAVTNALREQLAREHRRRQTDQIAQRLLKIGGRYAALPDTGRTPDEILGYDENG
LPT

Nucleotide

• Length: 252 bp

>AT128269 NZ_CP041387:3482391-3482642 [Rhodopseudomonas palustris]
ATGCATCTCAACATCAAGAACGACGAAGCTCATCAGTTAGCGACAGAGCTGGCCCGCATGACCGGGGAGAGCCTCACTGC
GGCGGTGACCAATGCGCTGCGCGAACAGCTCGCACGCGAGCATCGTCGCCGGCAAACCGACCAGATCGCGCAACGACTGC
TGAAGATCGGGGGCCGTTACGCCGCGTTGCCTGACACCGGGCGAACTCCAGACGAGATTCTCGGCTACGATGAGAATGGA
TTGCCCACGTGA

Structures

Antitoxin

• AlphaFold DB: Q6N2A9