Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 2799428..2800059 Replicon chromosome
Accession NZ_CP041387
Organism Rhodopseudomonas palustris strain GJ-22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FLL57_RS12825 Protein ID WP_142883086.1
Coordinates 2799428..2799832 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FLL57_RS12830 Protein ID WP_013501647.1
Coordinates 2799829..2800059 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLL57_RS12810 2794460..2794705 - 246 WP_013501651.1 hypothetical protein -
FLL57_RS12815 2795028..2796245 + 1218 WP_142883084.1 efflux RND transporter periplasmic adaptor subunit -
FLL57_RS12820 2796248..2799382 + 3135 WP_142883085.1 multidrug efflux RND transporter permease subunit -
FLL57_RS12825 2799428..2799832 - 405 WP_142883086.1 PIN domain-containing protein Toxin
FLL57_RS12830 2799829..2800059 - 231 WP_013501647.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FLL57_RS12840 2800510..2800923 + 414 WP_013501635.1 nucleotidyltransferase substrate binding protein -
FLL57_RS12845 2800920..2801252 + 333 WP_142883087.1 nucleotidyltransferase domain-containing protein -
FLL57_RS12850 2801265..2802458 - 1194 WP_142883088.1 CoA transferase -
FLL57_RS12855 2802587..2803909 - 1323 WP_047310112.1 TRAP transporter large permease subunit -
FLL57_RS12860 2803924..2804466 - 543 WP_013501631.1 TRAP transporter small permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

SpoVT-AbrB domain

(5-44)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14341.34 Da        Isoelectric Point: 5.6374

>T128268 WP_142883086.1 NZ_CP041387:c2799832-2799428 [Rhodopseudomonas palustris]
VTAFFDTNILVYAQETGAKADRARAVLGGGGRLSVQVLNEFTVVVQRKLGRGWREIAEAIDDALAVSGPPLPLTHDLHVA
ARVLAETCKLSFYDALIVAAAKEAGCDVLYSEDLQHGRSFGTLRVENPFLAGTT

Download         Length: 405 bp

>T128268 NZ_CP041387:c2799832-2799428 [Rhodopseudomonas palustris]
GTGACGGCTTTCTTCGATACTAACATTCTAGTCTATGCTCAGGAAACGGGCGCGAAAGCGGACCGTGCACGGGCCGTCTT
GGGCGGCGGTGGCAGGCTCAGCGTTCAAGTCTTGAACGAGTTCACCGTCGTGGTGCAGCGCAAGCTCGGCCGGGGGTGGA
GGGAGATCGCCGAGGCTATCGACGACGCTCTGGCTGTGTCAGGGCCGCCACTGCCTCTGACGCACGATCTGCACGTTGCC
GCTCGCGTGCTCGCTGAGACGTGCAAGCTGTCCTTCTACGACGCGCTGATCGTCGCGGCCGCCAAAGAGGCCGGGTGCGA
TGTGCTGTACAGCGAAGACCTGCAGCACGGCCGTAGCTTCGGCACGCTGCGTGTTGAAAATCCATTCCTTGCGGGCACGA
CGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8940.17 Da        Isoelectric Point: 5.2392

>AT128268 WP_013501647.1 NZ_CP041387:c2800059-2799829 [Rhodopseudomonas palustris]
MKVSRWGNSLAVRLPTALVDKLDLQEGDELNVVDVVERTLVVEKEDRRKAALERMAERKWKLPEGYRFDRDEANER

Download         Length: 231 bp

>AT128268 NZ_CP041387:c2800059-2799829 [Rhodopseudomonas palustris]
ATGAAGGTCTCCAGATGGGGCAATAGCCTCGCCGTCAGGCTGCCCACTGCGCTGGTGGACAAACTCGATCTGCAAGAGGG
CGACGAGCTGAACGTGGTCGACGTCGTCGAACGGACGCTGGTGGTCGAGAAGGAAGACAGGAGGAAAGCCGCGCTGGAGC
GCATGGCCGAGCGCAAGTGGAAGTTGCCCGAGGGCTATCGCTTCGATCGTGACGAGGCCAATGAGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References