Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2517797..2518486 Replicon chromosome
Accession NZ_CP041387
Organism Rhodopseudomonas palustris strain GJ-22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FLL57_RS11480 Protein ID WP_047308695.1
Coordinates 2518064..2518486 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FLL57_RS11475 Protein ID WP_142882949.1
Coordinates 2517797..2518051 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLL57_RS11455 2513121..2513909 - 789 WP_142882946.1 ATPase -
FLL57_RS11460 2513928..2514317 - 390 WP_052960643.1 hypothetical protein -
FLL57_RS11465 2514460..2515815 - 1356 WP_142882947.1 RluA family pseudouridine synthase -
FLL57_RS11470 2516625..2517305 + 681 WP_142882948.1 hypothetical protein -
FLL57_RS11475 2517797..2518051 + 255 WP_142882949.1 plasmid stabilization protein Antitoxin
FLL57_RS11480 2518064..2518486 + 423 WP_047308695.1 type II toxin-antitoxin system VapC family toxin Toxin
FLL57_RS11485 2518648..2519223 - 576 WP_142882950.1 HXXEE domain-containing protein -
FLL57_RS11490 2519687..2520661 + 975 WP_142882951.1 DUF4892 domain-containing protein -
FLL57_RS11495 2520875..2521552 + 678 WP_142882952.1 nitroreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14812.84 Da        Isoelectric Point: 4.8187

>T128267 WP_047308695.1 NZ_CP041387:2518064-2518486 [Rhodopseudomonas palustris]
MIVLDTNVVSEAMTREPHPRVREWLNAQSAETLFLSSITVAELLFGVSVLPAGKRKNALGAALDDVLDVFATRILPFDTP
AAQRYADLAVKARAAGKGFPTPDGYIAAIATAHGFAVASRDASAFDAAGLTVIDPWTTND

Download         Length: 423 bp

>T128267 NZ_CP041387:2518064-2518486 [Rhodopseudomonas palustris]
ATGATCGTGCTGGACACCAACGTCGTCTCCGAAGCGATGACGCGCGAACCGCATCCGCGGGTGCGCGAATGGCTCAATGC
TCAGTCCGCCGAGACTTTGTTCCTGTCCAGCATCACCGTCGCCGAACTTCTGTTCGGCGTTAGCGTCTTGCCGGCCGGAA
AGCGTAAGAACGCCTTGGGCGCTGCGCTCGACGATGTGTTGGACGTGTTTGCCACCCGCATCCTGCCGTTCGATACCCCG
GCTGCGCAGCGCTATGCCGATCTCGCCGTCAAGGCGCGCGCGGCCGGCAAGGGCTTCCCCACGCCCGACGGCTACATCGC
CGCGATCGCCACCGCGCACGGGTTCGCTGTCGCGTCGCGCGACGCGAGTGCGTTCGACGCCGCCGGTCTGACCGTGATCG
ATCCCTGGACCACAAATGACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9435.86 Da        Isoelectric Point: 8.6794

>AT128267 WP_142882949.1 NZ_CP041387:2517797-2518051 [Rhodopseudomonas palustris]
MVAVTIRNLSEEAHRALKVRAAQHNRSAEAEMRAILEAAVRPEGRLLLGTALQEIGQKYDITNADIEAIEQVRDKRPAKP
MKFE

Download         Length: 255 bp

>AT128267 NZ_CP041387:2517797-2518051 [Rhodopseudomonas palustris]
ATGGTCGCCGTCACCATTCGCAACCTCTCCGAGGAGGCGCATCGCGCCCTGAAGGTCCGCGCGGCGCAGCATAATCGCAG
CGCGGAAGCGGAGATGCGCGCCATTCTGGAAGCCGCGGTCCGCCCCGAGGGCCGCTTGCTGCTCGGCACGGCTTTGCAGG
AGATCGGGCAGAAATACGACATCACCAATGCTGATATCGAAGCCATCGAACAGGTCCGAGACAAGCGTCCTGCCAAGCCG
ATGAAGTTTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References