Detailed information of TA system TA128266

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 1975389..1976023
• Replicon: chromosome
• Accession: NZ_CP041387
• Organism: Rhodopseudomonas palustris strain GJ-22

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: FLL57_RS08995
• Protein ID: WP_013502482.1
• Coordinates: 1975389..1975769 (-)
• Length: 127 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: FLL57_RS09000
• Protein ID: WP_013502481.1
• Coordinates: 1975769..1976023 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FLL57_RS08955	1970841..1971359	+	519	WP_013502490.1	MarR family winged helix-turn-helix transcriptional regulator	-
FLL57_RS08960	1971575..1971802	+	228	WP_013502489.1	hypothetical protein	-
FLL57_RS08965	1971819..1972034	+	216	WP_013502488.1	hypothetical protein	-
FLL57_RS08970	1972050..1972622	+	573	WP_013502487.1	DUF4142 domain-containing protein	-
FLL57_RS08975	1972704..1973105	+	402	WP_047307936.1	group III truncated hemoglobin	-
FLL57_RS08980	1973297..1974175	-	879	WP_013502485.1	glutathione-dependent disulfide-bond oxidoreductase	-
FLL57_RS08985	1974449..1974655	+	207	WP_013502484.1	hypothetical protein	-
FLL57_RS08990	1974841..1975206	-	366	WP_013502483.1	cupin domain-containing protein	-
FLL57_RS08995	1975389..1975769	-	381	WP_013502482.1	type II toxin-antitoxin system VapC family toxin	Toxin
FLL57_RS09000	1975769..1976023	-	255	WP_013502481.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
FLL57_RS09005	1976273..1977571	+	1299	WP_142882702.1	serine hydroxymethyltransferase	-
FLL57_RS09010	1977717..1978199	+	483	WP_013502479.1	transcriptional regulator NrdR	-
FLL57_RS09015	1978196..1979365	+	1170	WP_142882703.1	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	-
FLL57_RS09020	1979376..1979984	+	609	WP_142882704.1	riboflavin synthase	-
FLL57_RS09025	1980200..1980691	+	492	WP_013502476.1	6,7-dimethyl-8-ribityllumazine synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-124)

Antitoxin

• Antitoxin VapB-like (1-83)

Sequences

Toxin

Protein

• Length: 127 a.a.
• Molecular weight: 13603.59 Da
• Isoelectric Point: 4.4420

>T128266 WP_013502482.1 NZ_CP041387:c1975769-1975389 [Rhodopseudomonas palustris]
MVIDTSVIVAIALDEPDAAALEARIADDPVRLISAATVLEATIVLETKLGDAGGREFDLWLLKIGAEIVPVDAEQMEAAR
RAWRRTGKGRHAADLNYGDCFAHALAITRGEPLLYKGEDFAKMEIG

Nucleotide

• Length: 381 bp

>T128266 NZ_CP041387:c1975769-1975389 [Rhodopseudomonas palustris]
ATGGTGATCGACACCTCCGTTATCGTGGCGATCGCGCTCGACGAGCCCGATGCCGCGGCGCTCGAGGCGCGGATCGCCGA
CGATCCGGTCCGCCTGATCTCCGCCGCCACCGTGCTCGAAGCGACGATCGTACTGGAGACGAAACTCGGCGATGCCGGCG
GACGCGAGTTCGACCTCTGGCTGCTCAAGATCGGCGCCGAGATCGTCCCGGTCGACGCCGAGCAGATGGAGGCCGCGCGC
CGCGCCTGGCGCCGCACCGGCAAAGGCCGCCACGCCGCCGACCTGAACTACGGCGACTGCTTCGCCCACGCCCTCGCGAT
CACGCGCGGCGAGCCGCTGCTTTACAAGGGCGAGGATTTTGCGAAGATGGAGATCGGTTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9665.92 Da
• Isoelectric Point: 8.7898

>AT128266 WP_013502481.1 NZ_CP041387:c1976023-1975769 [Rhodopseudomonas palustris]
MALSIKDPETERLARHLAQATGETITQATRRALEERLRRVGGQSRRAELLEDMAAIRQRWRAMPVRDDRTADEIVGYDEH
GLPR

Nucleotide

• Length: 255 bp

>AT128266 NZ_CP041387:c1976023-1975769 [Rhodopseudomonas palustris]
ATGGCGTTGAGCATCAAGGACCCTGAGACCGAGCGGCTGGCGCGCCATCTCGCGCAAGCGACCGGCGAAACCATCACCCA
GGCGACCAGGCGCGCGCTGGAAGAGCGGCTACGCCGGGTCGGCGGACAATCCCGCCGCGCCGAGCTGCTGGAGGACATGG
CGGCGATCCGCCAGCGCTGGCGCGCGATGCCGGTCCGCGACGACCGGACCGCGGACGAGATCGTCGGCTACGACGAGCAC
GGCTTGCCGCGCTGA