Detailed information of TA system TA128265

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/Tad-HTH_37
• Location: 1541376..1542132
• Replicon: chromosome
• Accession: NZ_CP041387
• Organism: Rhodopseudomonas palustris strain GJ-22

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: FLL57_RS07015
• Protein ID: WP_142882502.1
• Coordinates: 1541376..1541813 (+)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: FLL57_RS07020
• Protein ID: WP_047310144.1
• Coordinates: 1541800..1542132 (+)
• Length: 111 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FLL57_RS06995	1536860..1537504	+	645	WP_013502927.1	DUF47 domain-containing protein	-
FLL57_RS07000	1537519..1538529	+	1011	WP_013502926.1	inorganic phosphate transporter	-
FLL57_RS07005	1538545..1538859	-	315	WP_013502925.1	quaternary ammonium compound efflux SMR transporter SugE	-
FLL57_RS07010	1539090..1540715	+	1626	WP_013502924.1	peptide chain release factor 3	-
FLL57_RS07015	1541376..1541813	+	438	WP_142882502.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FLL57_RS07020	1541800..1542132	+	333	WP_047310144.1	helix-turn-helix domain-containing protein	Antitoxin
FLL57_RS07025	1542146..1542604	-	459	WP_142882503.1	SRPBCC family protein	-
FLL57_RS07030	1542801..1543958	-	1158	WP_142882504.1	hypothetical protein	-
FLL57_RS07035	1544124..1544582	-	459	WP_142882505.1	SRPBCC family protein	-
FLL57_RS07040	1544897..1546204	+	1308	WP_185966196.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (39-131)

Antitoxin

• HigA2-like, helix-turn-helix domain (11-90)

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 16339.96 Da
• Isoelectric Point: 10.4451

>T128265 WP_142882502.1 NZ_CP041387:1541376-1541813 [Rhodopseudomonas palustris]
MRVSCAVRLEIHLYSYLYRPAVSDDLPKRLVWIASSRRDMQTLPKSIRRSFGTALFAAQMGVAPPIAKVLKGFGGAGVLE
LIEDDRSGTYRAVYTVRFATAVYVLHVFQKKSKQGIATPHQDIELVRSRLKVAEELHRKADHENS

Nucleotide

• Length: 438 bp

>T128265 NZ_CP041387:1541376-1541813 [Rhodopseudomonas palustris]
ATGCGCGTTTCCTGCGCTGTCAGGCTTGAAATCCATTTATATAGTTATTTATATAGGCCGGCTGTGTCCGACGATCTTCC
GAAGCGCTTGGTCTGGATCGCATCCAGCCGCCGCGACATGCAGACTCTTCCGAAGAGCATTCGCCGGAGCTTCGGCACGG
CGCTGTTCGCGGCGCAGATGGGCGTAGCGCCGCCCATCGCCAAGGTGCTGAAGGGGTTCGGCGGCGCCGGCGTGTTGGAG
TTGATTGAAGACGATCGCAGCGGGACGTACCGCGCGGTCTATACGGTGCGCTTCGCGACGGCGGTCTACGTACTACACGT
TTTCCAGAAGAAGTCGAAACAGGGCATCGCGACACCGCATCAAGATATCGAGCTGGTCCGATCGCGATTGAAGGTCGCTG
AAGAATTGCACAGGAAGGCCGACCATGAAAACTCATGA

Antitoxin

Protein

• Length: 111 a.a.
• Molecular weight: 11772.79 Da
• Isoelectric Point: 10.4762

>AT128265 WP_047310144.1 NZ_CP041387:1541800-1542132 [Rhodopseudomonas palustris]
MKTHEISSGNVFADLGFADSEQELVKAKLTVQIYKLLSERCMTQGAAAKLLGTTQPQVSALMRCRPTSISVGRLMEFLTL
LGQDVQVTVKPAPRRKAAGGAGRLSVVVQA

Nucleotide

• Length: 333 bp

>AT128265 NZ_CP041387:1541800-1542132 [Rhodopseudomonas palustris]
ATGAAAACTCATGAAATCAGCAGCGGCAACGTATTCGCCGATCTCGGCTTTGCCGACTCCGAACAGGAATTGGTTAAGGC
CAAGCTGACGGTGCAGATCTACAAACTTCTCTCCGAACGCTGCATGACGCAGGGGGCGGCGGCGAAGCTTCTCGGCACCA
CGCAGCCGCAAGTCTCGGCGCTGATGCGCTGTCGGCCGACGTCGATCTCGGTCGGACGACTGATGGAATTTCTGACTCTG
CTTGGGCAGGACGTGCAGGTCACTGTGAAGCCCGCTCCGCGCCGGAAAGCGGCGGGCGGGGCGGGGCGTTTGTCGGTCGT
GGTGCAGGCTTAG