Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1311309..1311979 Replicon chromosome
Accession NZ_CP041387
Organism Rhodopseudomonas palustris strain GJ-22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FLL57_RS05940 Protein ID WP_142882389.1
Coordinates 1311309..1311719 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FLL57_RS05945 Protein ID WP_041807975.1
Coordinates 1311716..1311979 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLL57_RS05920 1306889..1308277 + 1389 WP_011157539.1 3-deoxy-7-phosphoheptulonate synthase class II -
FLL57_RS05925 1308408..1308761 + 354 WP_142882386.1 diacylglycerol kinase -
FLL57_RS05930 1308808..1310565 + 1758 WP_142882387.1 NAD+ synthase -
FLL57_RS05935 1310590..1311165 - 576 WP_142882388.1 hypothetical protein -
FLL57_RS05940 1311309..1311719 - 411 WP_142882389.1 type II toxin-antitoxin system VapC family toxin Toxin
FLL57_RS05945 1311716..1311979 - 264 WP_041807975.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FLL57_RS05950 1312175..1312915 + 741 WP_041807408.1 helix-turn-helix transcriptional regulator -
FLL57_RS05955 1312940..1314274 - 1335 WP_013503199.1 FAD-dependent oxidoreductase -
FLL57_RS05960 1314372..1315523 - 1152 WP_013503198.1 DUF2865 domain-containing protein -
FLL57_RS05965 1315712..1316020 - 309 WP_142882390.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1072466..1320120 247654


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(9-55)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15163.55 Da        Isoelectric Point: 5.6944

>T128264 WP_142882389.1 NZ_CP041387:c1311719-1311309 [Rhodopseudomonas palustris]
MSGWMLDTNVASHVIRGDKREIIERLVALPISDVVISSITEAELLYGLAKRGYPTALSERVREFLLRVDVLPWDHEVTKT
YAELRAACEAKGVTLSPLDMMIAAHAAATDAKLVTRDKAFSRVPSPLRIEDWAEMN

Download         Length: 411 bp

>T128264 NZ_CP041387:c1311719-1311309 [Rhodopseudomonas palustris]
ATGAGCGGCTGGATGCTGGATACCAATGTCGCCAGCCATGTCATCAGAGGCGATAAGCGCGAGATCATCGAGCGACTGGT
CGCGCTGCCCATCTCGGACGTCGTGATCTCGTCGATCACCGAAGCCGAACTCCTCTACGGCCTCGCTAAGCGAGGCTATC
CCACTGCGCTGTCCGAACGGGTTCGCGAATTCCTGCTCCGAGTCGACGTCCTGCCCTGGGATCACGAGGTGACCAAGACC
TACGCCGAGCTACGCGCCGCCTGCGAAGCCAAAGGCGTCACGCTCTCTCCTCTCGACATGATGATCGCAGCTCATGCTGC
CGCGACAGACGCGAAGCTAGTGACGCGAGACAAGGCTTTCAGCCGCGTGCCTTCGCCCTTACGGATCGAGGATTGGGCGG
AGATGAATTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9951.10 Da        Isoelectric Point: 5.1283

>AT128264 WP_041807975.1 NZ_CP041387:c1311979-1311716 [Rhodopseudomonas palustris]
MTSRTAKIFTTGRSQAVRLPAEFRFEGSEVFVRRDQKTGDVILSRKPDSWDGLLELHKTTAVPDDFMGPPDRTQPPQDRD
PFEGWTE

Download         Length: 264 bp

>AT128264 NZ_CP041387:c1311979-1311716 [Rhodopseudomonas palustris]
ATGACGTCCCGAACCGCCAAGATTTTCACGACCGGCCGCAGCCAGGCCGTCAGGCTCCCCGCGGAGTTTCGCTTCGAAGG
CAGCGAGGTTTTCGTGCGCCGCGACCAGAAGACGGGTGATGTCATCCTGTCCCGCAAGCCGGACTCCTGGGACGGTCTGC
TGGAGCTCCACAAGACAACAGCAGTGCCTGACGACTTCATGGGGCCGCCCGACCGCACCCAGCCGCCGCAGGATCGCGAT
CCGTTCGAAGGCTGGACCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References