Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 385030..385604 Replicon chromosome
Accession NZ_CP041387
Organism Rhodopseudomonas palustris strain GJ-22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FLL57_RS01805 Protein ID WP_047308981.1
Coordinates 385236..385604 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A336JL66
Locus tag FLL57_RS01800 Protein ID WP_047308980.1
Coordinates 385030..385236 (+) Length 69 a.a.

Genomic Context

FLL57_RS01765FLL57_RS01770FLL57_RS01780FLL57_RS01785FLL57_RS01795FLL57_RS01800FLL57_RS01805FLL57_RS01810FLL57_RS01815FLL57_RS01820FLL57_RS01825FLL57_RS01830FLL57_RS01835
Location: 381011..381757 (747 bp)
Type: Others
Protein ID: WP_013501043.1
Location: 382032..382553 (522 bp)
Type: Others
Protein ID: WP_047307674.1
Location: 382720..383337 (618 bp)
Type: Others
Protein ID: WP_142881970.1
Location: 383334..383759 (426 bp)
Type: Others
Protein ID: WP_142881971.1
Location: 383928..384971 (1044 bp)
Type: Others
Protein ID: WP_142881972.1
Location: 385030..385236 (207 bp)
Type: Antitoxin
Protein ID: WP_047308980.1
Location: 385236..385604 (369 bp)
Type: Toxin
Protein ID: WP_047308981.1
Location: 385609..386055 (447 bp)
Type: Others
Protein ID: WP_013501049.1
Location: 386153..387463 (1311 bp)
Type: Others
Protein ID: WP_013501050.1
Location: 387574..388824 (1251 bp)
Type: Others
Protein ID: WP_142881973.1
Location: 388882..389349 (468 bp)
Type: Others
Protein ID: WP_013501052.1
Location: 389368..389913 (546 bp)
Type: Others
Protein ID: WP_013501053.1
Location: 390104..390475 (372 bp)
Type: Others
Protein ID: WP_142884146.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FLL57_RS01765381011..381757+747WP_013501043.1YebC/PmpR family DNA-binding transcriptional regulator-
FLL57_RS01770382032..382553+522WP_047307674.1crossover junction endodeoxyribonuclease RuvC-
FLL57_RS01780382720..383337+618WP_142881970.1Holliday junction branch migration protein RuvA-
FLL57_RS01785383334..383759+426WP_142881971.1cytidine deaminase-
FLL57_RS01795383928..384971+1044WP_142881972.1Holliday junction branch migration DNA helicase RuvB-
FLL57_RS01800385030..385236+207WP_047308980.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
FLL57_RS01805385236..385604+369WP_047308981.1type II toxin-antitoxin system VapC family toxinToxin
FLL57_RS01810385609..386055+447WP_013501049.1tol-pal system-associated acyl-CoA thioesterase-
FLL57_RS01815386153..387463+1311WP_013501050.1NAD(P)/FAD-dependent oxidoreductase-
FLL57_RS01820387574..388824+1251WP_142881973.1OpgC domain-containing protein-
FLL57_RS01825388882..389349+468WP_013501052.1nuclear transport factor 2 family protein-
FLL57_RS01830389368..389913+546WP_013501053.1TetR/AcrR family transcriptional regulator-
FLL57_RS01835390104..390475+372WP_142884146.1YciI family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13211.19 Da        Isoelectric Point: 5.1123

>T128263 WP_047308981.1 NZ_CP041387:385236-385604 [Rhodopseudomonas palustris]
MLLVDTSIWIDHFRKGDSTLSAALGREEVLVHAFVLGELALGHNVHFEMIATDLSDLPQATIAVPGEVLRLISRAELAGS
GIGYVDAHLVASTLLTPEAQLWTRDKRLKAVADRLSISAQVE

Download         Length: 369 bp

>T128263 NZ_CP041387:385236-385604 [Rhodopseudomonas palustris]
ATGCTCCTGGTCGACACATCGATCTGGATCGACCATTTCCGCAAGGGAGACTCGACGCTCAGCGCCGCTCTTGGTCGGGA
AGAGGTCCTGGTCCATGCTTTTGTTCTGGGCGAGTTAGCGCTGGGCCATAACGTTCACTTTGAGATGATCGCGACCGACC
TTTCGGACCTTCCTCAAGCGACGATTGCGGTGCCTGGTGAGGTATTGCGGCTCATTTCGCGCGCCGAGCTGGCCGGCTCG
GGAATCGGCTACGTGGATGCACATCTAGTCGCTTCGACGCTGCTGACGCCTGAGGCGCAGCTATGGACGCGCGATAAGAG
ATTAAAAGCGGTGGCCGATCGACTATCGATCTCCGCCCAAGTGGAGTGA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7565.72 Da        Isoelectric Point: 10.8025

>AT128263 WP_047308980.1 NZ_CP041387:385030-385236 [Rhodopseudomonas palustris]
MRTTIAIDDELFAKAQKFAGLDEKSAVIKTALQAYVEREAARRLARMGGSMPDAKAPPRRRSPKFTND

Download         Length: 207 bp

>AT128263 NZ_CP041387:385030-385236 [Rhodopseudomonas palustris]
ATGAGAACGACGATTGCCATCGACGATGAGTTGTTTGCGAAAGCTCAGAAATTTGCAGGCCTCGACGAAAAGTCCGCAGT
GATCAAGACGGCGCTGCAGGCCTATGTCGAACGTGAAGCAGCGAGGCGACTTGCGCGCATGGGTGGGTCGATGCCCGATG
CCAAGGCGCCCCCGCGTCGGCGCTCACCCAAATTCACCAACGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A336JL66

References