Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2017003..2017148 | Replicon | chromosome |
| Accession | NZ_CP041373 | ||
| Organism | Klebsiella pneumoniae strain KP58 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2017039..2017141 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2017003..2017148 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FM021_RS10035 | 2012133..2014193 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| FM021_RS10040 | 2014197..2014856 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| FM021_RS10045 | 2014935..2015165 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FM021_RS10050 | 2015278..2015652 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| FM021_RS10055 | 2015656..2016525 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| FM021_RS10060 | 2016542..2016880 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2017003..2017148 | - | 146 | - | - | Antitoxin |
| - | 2017039..2017141 | + | 103 | - | - | Toxin |
| FM021_RS10070 | 2017516..2017659 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| FM021_RS10075 | 2017764..2018732 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| FM021_RS10080 | 2018889..2019542 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| FM021_RS10085 | 2019539..2019730 | - | 192 | WP_002911395.1 | YebW family protein | - |
| FM021_RS10090 | 2019828..2020067 | - | 240 | WP_002911393.1 | YebV family protein | - |
| FM021_RS10095 | 2020183..2021616 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T128239 NZ_CP041373:2017039-2017141 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT128239 NZ_CP041373:c2017148-2017003 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
