Detailed information of TA system TA128233

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/RelE-RHH
• Location: 5936..6492
• Replicon: plasmid p1
• Accession: NZ_CP041366
• Organism: Acinetobacter tandoii strain SE63

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: FM020_RS16725
• Protein ID: WP_142770113.1
• Coordinates: 6220..6492 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: FM020_RS16720
• Protein ID: WP_142770112.1
• Coordinates: 5936..6220 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FM020_RS16700	1261..2181	-	921	WP_142770109.1	replication initiation protein RepM	-
FM020_RS16710	4264..5301	+	1038	WP_142770110.1	hypothetical protein	-
FM020_RS16715	5305..5823	-	519	WP_142770111.1	hypothetical protein	-
FM020_RS16720	5936..6220	+	285	WP_142770112.1	hypothetical protein	Antitoxin
FM020_RS16725	6220..6492	+	273	WP_142770113.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FM020_RS16730	6756..8183	+	1428	WP_142770114.1	DUF1254 domain-containing protein	-
FM020_RS16735	8812..9168	+	357	WP_142770115.1	type II toxin-antitoxin system RelE/ParE family toxin	-
FM020_RS16740	9161..9463	+	303	WP_055414414.1	XRE family transcriptional regulator	-
FM020_RS16745	9590..11125	-	1536	WP_142770116.1	arylsulfatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..11449	11449

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10309.88 Da
• Isoelectric Point: 5.9616

>T128233 WP_142770113.1 NZ_CP041366:6220-6492 [Acinetobacter tandoii]
MKVFWTPTALDDLERIIDYIAERNLVAAIELHALIEEKTDLLSHSSLMGRSGLVTGTRELVVHPHYVVVYDVKDTVRILR
VLHTSQQWEG

Nucleotide

• Length: 273 bp

>T128233 NZ_CP041366:6220-6492 [Acinetobacter tandoii]
ATGAAAGTGTTTTGGACACCGACTGCTTTAGACGATTTAGAGCGAATTATTGATTATATTGCCGAGCGTAATTTGGTTGC
TGCGATTGAATTGCACGCTTTGATTGAAGAAAAAACGGATTTGCTTTCTCACAGTAGCCTGATGGGGCGATCTGGTCTGG
TCACTGGTACGCGTGAATTGGTGGTTCATCCACACTATGTTGTGGTGTATGACGTTAAAGACACGGTTCGTATTTTAAGA
GTTCTGCATACATCACAGCAGTGGGAAGGTTAA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10754.17 Da
• Isoelectric Point: 6.3709

>AT128233 WP_142770112.1 NZ_CP041366:5936-6220 [Acinetobacter tandoii]
MAEATFTFRVEESLKKEFSSFAKDMDRSGAQLLRDFMRDFVKQQQEAASYDAWYQKQVQIGLDEANAGQLVPQEEVKSRF
EAKRASLLAKLAAK

Nucleotide

• Length: 285 bp

>AT128233 NZ_CP041366:5936-6220 [Acinetobacter tandoii]
ATGGCAGAAGCGACTTTCACATTCCGCGTAGAGGAATCCTTGAAGAAAGAATTTTCTAGTTTTGCGAAGGATATGGACCG
TAGCGGAGCGCAATTATTGCGTGACTTCATGCGTGATTTTGTGAAGCAACAGCAAGAAGCTGCATCCTATGATGCGTGGT
ATCAAAAACAGGTCCAAATTGGCTTAGATGAAGCCAATGCAGGGCAATTGGTGCCACAAGAAGAAGTCAAATCTCGTTTT
GAAGCAAAACGTGCCAGTTTACTGGCTAAATTGGCAGCCAAATAA