Detailed information of TA system TA128212

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yjhX-yjhQ/YjhX-GNAT
• Location: 1903176..1903995
• Replicon: chromosome
• Accession: NZ_CP041362
• Organism: Citrobacter amalonaticus strain 133355-SW-C4-Cam

Toxin (Protein)

• Gene name: yjhX
• Uniprot ID: -
• Locus tag: FEO47_RS08930
• Protein ID: WP_142765038.1
• Coordinates: 1903176..1903433 (+)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: yjhQ
• Uniprot ID: -
• Locus tag: FEO47_RS08935
• Protein ID: WP_142765039.1
• Coordinates: 1903444..1903995 (+)
• Length: 184 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FEO47_RS08905	1898982..1899887	-	906	WP_043001082.1	dihydrodipicolinate synthase family protein	-
FEO47_RS08910	1899892..1900680	-	789	WP_142765035.1	IclR family transcriptional regulator	-
FEO47_RS08915	1900916..1901707	+	792	WP_142765036.1	PhzF family phenazine biosynthesis protein	-
FEO47_RS08920	1902188..1902580	+	393	WP_142765037.1	VOC family protein	-
FEO47_RS08925	1902590..1902796	+	207	WP_054177313.1	tryptophan synthase subunit alpha	-
FEO47_RS08930	1903176..1903433	+	258	WP_142765038.1	YjhX family toxin	Toxin
FEO47_RS08935	1903444..1903995	+	552	WP_142765039.1	N-acetyltransferase	Antitoxin
FEO47_RS08940	1904047..1904793	+	747	WP_090050577.1	class I SAM-dependent methyltransferase	-
FEO47_RS08945	1905470..1906054	+	585	WP_044264020.1	hypothetical protein	-
FEO47_RS08950	1906364..1907488	-	1125	WP_142765040.1	N-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Putative toxin of bacterial toxin-antitoxin pair (1-85)

Antitoxin

• GNAT domain (18-121)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 9475.97 Da
• Isoelectric Point: 11.1381

>T128212 WP_142765038.1 NZ_CP041362:1903176-1903433 [Citrobacter amalonaticus]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTAVECYSREGLLLADCTLAVFKKLKTKKLIKSVNGQPYRINSTGLNNVRA
QPDNR

Nucleotide

• Length: 258 bp

>T128212 NZ_CP041362:1903176-1903433 [Citrobacter amalonaticus]
ATGAATTTATCCCGTCAGGAACAACGTACCTTACACGTTCTCGCCAAAGGTGGACGTATTGCGCACGTCCGCGATGCGTC
AGGCCGCGTCACCGCCGTTGAATGCTACAGCCGCGAAGGGCTGCTGCTCGCCGACTGTACACTTGCCGTCTTCAAAAAAC
TCAAAACCAAAAAGCTGATCAAATCCGTCAATGGTCAGCCGTACCGCATTAATAGCACCGGGCTGAACAACGTGCGTGCT
CAGCCAGATAACCGCTAA

Antitoxin

Protein

• Length: 184 a.a.
• Molecular weight: 20364.26 Da
• Isoelectric Point: 6.2852

>AT128212 WP_142765039.1 NZ_CP041362:1903444-1903995 [Citrobacter amalonaticus]
MTTRNFTIHITNESDTNDIREVETRAFGYSKEACLVASLLEDDTARPTLSLLARQEGNAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGRGVGGLLIRTGIEHLRSMGCQCVFVLGHATYYPRHGFEPCAGDKGFPAPYPIAEEHKACWMMQSLSA
QPFDRAGDIQCAQALMKPEHWRE

Nucleotide

• Length: 552 bp

>AT128212 NZ_CP041362:1903444-1903995 [Citrobacter amalonaticus]
ATGACAACACGCAACTTCACTATTCATATTACCAATGAAAGTGATACCAACGACATCCGGGAAGTCGAAACCCGCGCCTT
TGGCTACAGTAAAGAGGCCTGCCTGGTGGCTTCTTTGCTCGAGGACGACACTGCGCGTCCAACGTTATCGTTGCTGGCCA
GACAGGAAGGTAACGCCGTCGGGCATATCCTGTTTACCCGGGCGACATTCAAAGGAGAAATGGATTCCCCTCTGATGCAT
ATCCTTGCTCCCCTGGCGGTCATCCCTGAATACCAGGGGAGGGGCGTGGGCGGATTATTGATTCGTACCGGTATAGAACA
CTTACGCTCGATGGGATGCCAGTGCGTTTTTGTTCTCGGTCATGCCACTTACTATCCGCGACATGGATTTGAACCCTGTG
CAGGAGACAAAGGCTTTCCCGCGCCTTACCCCATTGCGGAGGAACATAAGGCCTGCTGGATGATGCAGTCCCTCTCCGCA
CAACCCTTTGATCGTGCCGGCGACATCCAATGTGCGCAGGCCTTAATGAAACCGGAGCACTGGCGTGAATAA