Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 2245375..2245883 | Replicon | chromosome |
Accession | NZ_CP041359 | ||
Organism | Escherichia coli strain U1 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | - |
Locus tag | E3Z32_RS12080 | Protein ID | WP_001534843.1 |
Coordinates | 2245375..2245584 (+) | Length | 70 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A0V9L4L3 |
Locus tag | E3Z32_RS12085 | Protein ID | WP_000063161.1 |
Coordinates | 2245581..2245883 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
E3Z32_RS12065 | 2241130..2242440 | - | 1311 | WP_001534837.1 | restriction endonuclease subunit S | - |
E3Z32_RS12070 | 2242430..2244049 | - | 1620 | WP_001550561.1 | type I restriction-modification system subunit M | - |
E3Z32_RS12075 | 2244113..2245279 | - | 1167 | WP_001534841.1 | restriction endonuclease | - |
E3Z32_RS12080 | 2245375..2245584 | + | 210 | WP_001534843.1 | BrnT family toxin | Toxin |
E3Z32_RS12085 | 2245581..2245883 | + | 303 | WP_000063161.1 | BrnA antitoxin family protein | Antitoxin |
E3Z32_RS12090 | 2245917..2246873 | - | 957 | WP_001534845.1 | GTPase | - |
E3Z32_RS12095 | 2246884..2247087 | - | 204 | WP_001534846.1 | YbdD/YjiX family protein | - |
E3Z32_RS12100 | 2247205..2249355 | - | 2151 | WP_001366791.1 | pyruvate/proton symporter BtsT | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 70 a.a. Molecular weight: 7952.17 Da Isoelectric Point: 4.9493
>T128184 WP_001534843.1 NZ_CP041359:2245375-2245584 [Escherichia coli]
MVDYPKRDAISNINAIIVDTFLYIQLGMATMPMEFEWNANKAKSNRVKHGIRFEDAVLVLDDPQRTEPL
MVDYPKRDAISNINAIIVDTFLYIQLGMATMPMEFEWNANKAKSNRVKHGIRFEDAVLVLDDPQRTEPL
Download Length: 210 bp
>T128184 NZ_CP041359:2245375-2245584 [Escherichia coli]
ATGGTTGATTATCCAAAACGTGATGCTATTTCCAACATCAACGCTATAATTGTAGATACATTTTTGTATATACAATTAGG
GATGGCAACTATGCCAATGGAGTTTGAATGGAATGCAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTG
AAGATGCGGTGTTAGTGCTTGATGATCCACAACGAACGGAGCCGCTATGA
ATGGTTGATTATCCAAAACGTGATGCTATTTCCAACATCAACGCTATAATTGTAGATACATTTTTGTATATACAATTAGG
GATGGCAACTATGCCAATGGAGTTTGAATGGAATGCAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTG
AAGATGCGGTGTTAGTGCTTGATGATCCACAACGAACGGAGCCGCTATGA
Antitoxin
Download Length: 101 a.a. Molecular weight: 11600.10 Da Isoelectric Point: 9.4646
>AT128184 WP_000063161.1 NZ_CP041359:2245581-2245883 [Escherichia coli]
MSMVKHKRGTSSTLDVQHEAELKVLANKFDEDIDYSDIPSSSDEQWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK
MSMVKHKRGTSSTLDVQHEAELKVLANKFDEDIDYSDIPSSSDEQWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK
Download Length: 303 bp
>AT128184 NZ_CP041359:2245581-2245883 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGTGCTGGCGAA
CAAATTCGACGAGGATATTGATTACAGCGACATCCCATCTTCCAGCGATGAGCAATGGTCTAACGCAGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGTGCTGGCGAA
CAAATTCGACGAGGATATTGATTACAGCGACATCCCATCTTCCAGCGATGAGCAATGGTCTAACGCAGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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